Pharmaceutical formulations containing vitamin e tpgs molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations

Compounds and compositions are disclosed for increasing the bioavailability of lipophilic drugs, and more specifically, to solubilizing lipophilic drugs using bioenhancers that cause no efflux inhibition or a desired degree of efflux inhibition. Methods of making and using such compositions are also...

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1. Verfasser: HYATT JOHN ANTHONY,ZIMA GEORGE CHESTER,EDGAR KEVIN JOSEPH,NAVARRO LISA TONNER,LEHR CLAUS-MICHAEL,COLLNOT EVA-MARIA,SINGLETON ANDY HUGH,BALDES CHRISTIANE,SCHAFER ULRICH FRIEDRICH,WEMPE MICHAEL FITZPATR
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creator HYATT JOHN ANTHONY,ZIMA GEORGE CHESTER,EDGAR KEVIN JOSEPH,NAVARRO LISA TONNER,LEHR CLAUS-MICHAEL,COLLNOT EVA-MARIA,SINGLETON ANDY HUGH,BALDES CHRISTIANE,SCHAFER ULRICH FRIEDRICH,WEMPE MICHAEL FITZPATR
description Compounds and compositions are disclosed for increasing the bioavailability of lipophilic drugs, and more specifically, to solubilizing lipophilic drugs using bioenhancers that cause no efflux inhibition or a desired degree of efflux inhibition. Methods of making and using such compositions are also disclosed.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Pharmaceutical formulations containing vitamin e tpgs molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations
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