Triazole compounds and their use as metabotropic glutamate receptor antagonists
The present invention relates to new compounds of formula (I), wherein P, Q, X , X , X , X X , X , R , R , R , m, n, and p are as defined as in formula (I), or salts, or hydrates thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositio...
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| creator | EDWARDS LOUISE,ISAAC METHVIN,JOHANSSON MARTIN,MALMBERG JOHAN,MINIDIS ALEXANDER,STAAF KARIN,SLASSI ABDELMALIK,WENSBO DAVID,STEFANAC TOMISLAV,XIN TAO |
| description | The present invention relates to new compounds of formula (I), wherein P, Q, X , X , X , X X , X , R , R , R , m, n, and p are as defined as in formula (I), or salts, or hydrates thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy, especially for the treatment of mGluR5 receptor mediated disorders, and for the treatment of neurological disorders, psychiatric disorders, gastrointestinal disorders and pain disorders. |
| format | Patent |
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JOHAN,MINIDIS ALEXANDER,STAAF KARIN,SLASSI ABDELMALIK,WENSBO DAVID,STEFANAC TOMISLAV,XIN TAO</creatorcontrib><description>The present invention relates to new compounds of formula (I), wherein P, Q, X , X , X , X X , X , R , R , R , m, n, and p are as defined as in formula (I), or salts, or hydrates thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy, especially for the treatment of mGluR5 receptor mediated disorders, and for the treatment of neurological disorders, psychiatric disorders, gastrointestinal disorders and pain disorders.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL 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metabotropic glutamate receptor antagonists</title><description>The present invention relates to new compounds of formula (I), wherein P, Q, X , X , X , X X , X , R , R , R , m, n, and p are as defined as in formula (I), or salts, or hydrates thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy, especially for the treatment of mGluR5 receptor mediated disorders, and for the treatment of neurological disorders, psychiatric disorders, gastrointestinal disorders and pain disorders.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF 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LOUISE,ISAAC METHVIN,JOHANSSON MARTIN,MALMBERG JOHAN,MINIDIS ALEXANDER,STAAF KARIN,SLASSI ABDELMALIK,WENSBO DAVID,STEFANAC TOMISLAV,XIN TAO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Triazole compounds and their use as metabotropic glutamate receptor antagonists</title><date>2007-08-15</date><risdate>2007</risdate><abstract>The present invention relates to new compounds of formula (I), wherein P, Q, X , X , X , X X , X , R , R , R , m, n, and p are as defined as in formula (I), or salts, or hydrates thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy, especially for the treatment of mGluR5 receptor mediated disorders, and for the treatment of neurological disorders, psychiatric disorders, gastrointestinal disorders and pain disorders.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Triazole compounds and their use as metabotropic glutamate receptor antagonists |
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