Agentes inhibidores de ask1
Se proporcionan compuestos de fórmula (I): que incluyen compuestos de las Fórmulas (II), (III) y (IV), donde X, R1, R2, R3 y n son tal como se definen en la presente, y sales farmacéuticamente aceptables de estos, y métodos para su uso y producción. Estos compuestos pueden ser útiles, por ejemplo, e...
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| creator | HIMMELBAUER, Martin GONZALEZ LOPEZ DE TURISO, Felix JONES, John, H DECHANTSREITER, Michael XIN, Zhili |
| description | Se proporcionan compuestos de fórmula (I): que incluyen compuestos de las Fórmulas (II), (III) y (IV), donde X, R1, R2, R3 y n son tal como se definen en la presente, y sales farmacéuticamente aceptables de estos, y métodos para su uso y producción. Estos compuestos pueden ser útiles, por ejemplo, en el tratamiento de trastornos que responden a la inhibición de la cinasa reguladora de las señales de apoptosis 1 (ASK1).
Provided are compounds of Formula (I):including compounds of Formulas (II), (III) and (IV), wherein X, R1, R2, R3 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorders responsive to the inhibition of apoptosis signal-regulating kinase 1 (ASK1). |
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Provided are compounds of Formula (I):including compounds of Formulas (II), (III) and (IV), wherein X, R1, R2, R3 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorders responsive to the inhibition of apoptosis signal-regulating kinase 1 (ASK1).</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210903&DB=EPODOC&CC=CL&NR=2020003375A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210903&DB=EPODOC&CC=CL&NR=2020003375A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HIMMELBAUER, Martin</creatorcontrib><creatorcontrib>GONZALEZ LOPEZ DE TURISO, Felix</creatorcontrib><creatorcontrib>JONES, John, H</creatorcontrib><creatorcontrib>DECHANTSREITER, Michael</creatorcontrib><creatorcontrib>XIN, Zhili</creatorcontrib><title>Agentes inhibidores de ask1</title><description>Se proporcionan compuestos de fórmula (I): que incluyen compuestos de las Fórmulas (II), (III) y (IV), donde X, R1, R2, R3 y n son tal como se definen en la presente, y sales farmacéuticamente aceptables de estos, y métodos para su uso y producción. Estos compuestos pueden ser útiles, por ejemplo, en el tratamiento de trastornos que responden a la inhibición de la cinasa reguladora de las señales de apoptosis 1 (ASK1).
Provided are compounds of Formula (I):including compounds of Formulas (II), (III) and (IV), wherein X, R1, R2, R3 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorders responsive to the inhibition of apoptosis signal-regulating kinase 1 (ASK1).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJB2TE_NK0ktVsjMy8hMykzJLwKyU1IVEouzDXkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSbyzj5GBkYGBgbGxuamjoTFxqgDRySOg</recordid><startdate>20210903</startdate><enddate>20210903</enddate><creator>HIMMELBAUER, Martin</creator><creator>GONZALEZ LOPEZ DE TURISO, Felix</creator><creator>JONES, John, H</creator><creator>DECHANTSREITER, Michael</creator><creator>XIN, Zhili</creator><scope>EVB</scope></search><sort><creationdate>20210903</creationdate><title>Agentes inhibidores de ask1</title><author>HIMMELBAUER, Martin ; GONZALEZ LOPEZ DE TURISO, Felix ; JONES, John, H ; DECHANTSREITER, Michael ; XIN, Zhili</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CL2020003375A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HIMMELBAUER, Martin</creatorcontrib><creatorcontrib>GONZALEZ LOPEZ DE TURISO, Felix</creatorcontrib><creatorcontrib>JONES, John, H</creatorcontrib><creatorcontrib>DECHANTSREITER, Michael</creatorcontrib><creatorcontrib>XIN, Zhili</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HIMMELBAUER, Martin</au><au>GONZALEZ LOPEZ DE TURISO, Felix</au><au>JONES, John, H</au><au>DECHANTSREITER, Michael</au><au>XIN, Zhili</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Agentes inhibidores de ask1</title><date>2021-09-03</date><risdate>2021</risdate><abstract>Se proporcionan compuestos de fórmula (I): que incluyen compuestos de las Fórmulas (II), (III) y (IV), donde X, R1, R2, R3 y n son tal como se definen en la presente, y sales farmacéuticamente aceptables de estos, y métodos para su uso y producción. Estos compuestos pueden ser útiles, por ejemplo, en el tratamiento de trastornos que responden a la inhibición de la cinasa reguladora de las señales de apoptosis 1 (ASK1).
Provided are compounds of Formula (I):including compounds of Formulas (II), (III) and (IV), wherein X, R1, R2, R3 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorders responsive to the inhibition of apoptosis signal-regulating kinase 1 (ASK1).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Agentes inhibidores de ask1 |
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