Dihidrooxadiazinonas
La invención proporciona compuestos de dihidrooxidiazinona de la fórmula general (I), en donde R1, R2, R3, y R4 son como se definen en el presente, procedimientos para la preparación de dichos compuestos, compuestos intermedios útiles para la preparación de dichos compuestos, composiciones farmacéut...
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creator | Dr. Charlotte Christine KOPITZ Timothy A. LEWIS Dr. Manuel ELLERMANN Dr. Detlev SÜLZLE Prof. Dr.Christa HEGELE-HARTUNG Dr. Philip LIENAU Dr. Martin LANGE Xiaoyun WU Alex BURGIN Prof. Matthew MEYERSON Dr. Stefan Nikolaus GRADL Dr. Adrian TERSTEEGEN Heidi GREULICH |
description | La invención proporciona compuestos de dihidrooxidiazinona de la fórmula general (I), en donde R1, R2, R3, y R4 son como se definen en el presente, procedimientos para la preparación de dichos compuestos, compuestos intermedios útiles para la preparación de dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la elaboración de composiciones farmacéuticas para el tratamiento o la profilaxis de enfermedades, en especial de enfermedades hiperproliferativas, como un único agente o en combinación con otros ingredientes activos.
The present invention provides dihydrooxydiazinone compounds of general formula (I)in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients. |
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The present invention provides dihydrooxydiazinone compounds of general formula (I)in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201113&DB=EPODOC&CC=CL&NR=2020000303A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201113&DB=EPODOC&CC=CL&NR=2020000303A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Dr. Charlotte Christine KOPITZ</creatorcontrib><creatorcontrib>Timothy A. LEWIS</creatorcontrib><creatorcontrib>Dr. Manuel ELLERMANN</creatorcontrib><creatorcontrib>Dr. Detlev SÜLZLE</creatorcontrib><creatorcontrib>Prof. Dr.Christa HEGELE-HARTUNG</creatorcontrib><creatorcontrib>Dr. Philip LIENAU</creatorcontrib><creatorcontrib>Dr. Martin LANGE</creatorcontrib><creatorcontrib>Xiaoyun WU</creatorcontrib><creatorcontrib>Alex BURGIN</creatorcontrib><creatorcontrib>Prof. Matthew MEYERSON</creatorcontrib><creatorcontrib>Dr. Stefan Nikolaus GRADL</creatorcontrib><creatorcontrib>Dr. Adrian TERSTEEGEN</creatorcontrib><creatorcontrib>Heidi GREULICH</creatorcontrib><title>Dihidrooxadiazinonas</title><description>La invención proporciona compuestos de dihidrooxidiazinona de la fórmula general (I), en donde R1, R2, R3, y R4 son como se definen en el presente, procedimientos para la preparación de dichos compuestos, compuestos intermedios útiles para la preparación de dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la elaboración de composiciones farmacéuticas para el tratamiento o la profilaxis de enfermedades, en especial de enfermedades hiperproliferativas, como un único agente o en combinación con otros ingredientes activos.
The present invention provides dihydrooxydiazinone compounds of general formula (I)in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBBxyczITCnKz69ITMlMrMrMy89LLOZhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHOPkYGRgZAYGxg7GhoTJwqAPQhIcw</recordid><startdate>20201113</startdate><enddate>20201113</enddate><creator>Dr. Charlotte Christine KOPITZ</creator><creator>Timothy A. LEWIS</creator><creator>Dr. Manuel ELLERMANN</creator><creator>Dr. Detlev SÜLZLE</creator><creator>Prof. Dr.Christa HEGELE-HARTUNG</creator><creator>Dr. Philip LIENAU</creator><creator>Dr. Martin LANGE</creator><creator>Xiaoyun WU</creator><creator>Alex BURGIN</creator><creator>Prof. Matthew MEYERSON</creator><creator>Dr. Stefan Nikolaus GRADL</creator><creator>Dr. Adrian TERSTEEGEN</creator><creator>Heidi GREULICH</creator><scope>EVB</scope></search><sort><creationdate>20201113</creationdate><title>Dihidrooxadiazinonas</title><author>Dr. Charlotte Christine KOPITZ ; Timothy A. LEWIS ; Dr. Manuel ELLERMANN ; Dr. Detlev SÜLZLE ; Prof. Dr.Christa HEGELE-HARTUNG ; Dr. Philip LIENAU ; Dr. Martin LANGE ; Xiaoyun WU ; Alex BURGIN ; Prof. Matthew MEYERSON ; Dr. Stefan Nikolaus GRADL ; Dr. Adrian TERSTEEGEN ; Heidi GREULICH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CL2020000303A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Dr. Charlotte Christine KOPITZ</creatorcontrib><creatorcontrib>Timothy A. LEWIS</creatorcontrib><creatorcontrib>Dr. Manuel ELLERMANN</creatorcontrib><creatorcontrib>Dr. Detlev SÜLZLE</creatorcontrib><creatorcontrib>Prof. Dr.Christa HEGELE-HARTUNG</creatorcontrib><creatorcontrib>Dr. Philip LIENAU</creatorcontrib><creatorcontrib>Dr. Martin LANGE</creatorcontrib><creatorcontrib>Xiaoyun WU</creatorcontrib><creatorcontrib>Alex BURGIN</creatorcontrib><creatorcontrib>Prof. Matthew MEYERSON</creatorcontrib><creatorcontrib>Dr. Stefan Nikolaus GRADL</creatorcontrib><creatorcontrib>Dr. Adrian TERSTEEGEN</creatorcontrib><creatorcontrib>Heidi GREULICH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Dr. Charlotte Christine KOPITZ</au><au>Timothy A. LEWIS</au><au>Dr. Manuel ELLERMANN</au><au>Dr. Detlev SÜLZLE</au><au>Prof. Dr.Christa HEGELE-HARTUNG</au><au>Dr. Philip LIENAU</au><au>Dr. Martin LANGE</au><au>Xiaoyun WU</au><au>Alex BURGIN</au><au>Prof. Matthew MEYERSON</au><au>Dr. Stefan Nikolaus GRADL</au><au>Dr. Adrian TERSTEEGEN</au><au>Heidi GREULICH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Dihidrooxadiazinonas</title><date>2020-11-13</date><risdate>2020</risdate><abstract>La invención proporciona compuestos de dihidrooxidiazinona de la fórmula general (I), en donde R1, R2, R3, y R4 son como se definen en el presente, procedimientos para la preparación de dichos compuestos, compuestos intermedios útiles para la preparación de dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la elaboración de composiciones farmacéuticas para el tratamiento o la profilaxis de enfermedades, en especial de enfermedades hiperproliferativas, como un único agente o en combinación con otros ingredientes activos.
The present invention provides dihydrooxydiazinone compounds of general formula (I)in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Dihidrooxadiazinonas |
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