Proceso para preparar una sal de cinconidina, inhibidor macrociclico de la proteasa del virus de la hepatitis c (hvc)

Disclosed is a process for the preparation of a cinchonidine salt of formula (IV) via an aqueous solution of a racemic 4-hydroxy-1,2-cyclopentanedicarboxylic acid, which is subjected to cyclization without removing water, by the addition of a water-miscible organic solvent to the aqueous solution an...

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Bibliographische Detailangaben

Hauptverfasser:	HORVATH, ANDRAS, DEPRÉ, DOMINIQUE PAUL MICHEL, ORMEROD, DOMINIC JOHN
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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