Compuestos derivados de heterociclos nitrogenados, antagonistas trpm8; composicion farmaceutica; y su uso en el tratamiento de la migraña, dolor agudo, inflamatorio o neuropatico, entre otros
Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders in...
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| creator | GORE, VIJAY KESHAV LIU, QINGYLAN HARRIED, SCOTT KALLER, MATTHEW R YUAN, CHESTER CHENGUANG MA, VU VAN CHEN, JIAN J ZHONG, WENG MONENSCHEIN, HOLGER BROWN, JAMES BISWAS, KAUSTAV HORNE, DANIEL B NGUYEN THOMAS T ST. JEAN, DAVID J., JR |
| description | Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein. |
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JEAN, DAVID J., JR</creator><creatorcontrib>GORE, VIJAY KESHAV ; LIU, QINGYLAN ; HARRIED, SCOTT ; KALLER, MATTHEW R ; YUAN, CHESTER CHENGUANG ; MA, VU VAN ; CHEN, JIAN J ; ZHONG, WENG ; MONENSCHEIN, HOLGER ; BROWN, JAMES ; BISWAS, KAUSTAV ; HORNE, DANIEL B ; NGUYEN THOMAS T ; ST. JEAN, DAVID J., JR</creatorcontrib><description>Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. 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JEAN, DAVID J., JR</creatorcontrib><title>Compuestos derivados de heterociclos nitrogenados, antagonistas trpm8; composicion farmaceutica; y su uso en el tratamiento de la migraña, dolor agudo, inflamatorio o neuropatico, entre otros</title><description>Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. 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JEAN, DAVID J., JR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GORE, VIJAY KESHAV</au><au>LIU, QINGYLAN</au><au>HARRIED, SCOTT</au><au>KALLER, MATTHEW R</au><au>YUAN, CHESTER CHENGUANG</au><au>MA, VU VAN</au><au>CHEN, JIAN J</au><au>ZHONG, WENG</au><au>MONENSCHEIN, HOLGER</au><au>BROWN, JAMES</au><au>BISWAS, KAUSTAV</au><au>HORNE, DANIEL B</au><au>NGUYEN THOMAS T</au><au>ST. JEAN, DAVID J., JR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Compuestos derivados de heterociclos nitrogenados, antagonistas trpm8; composicion farmaceutica; y su uso en el tratamiento de la migraña, dolor agudo, inflamatorio o neuropatico, entre otros</title><date>2014-06-27</date><risdate>2014</risdate><abstract>Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Compuestos derivados de heterociclos nitrogenados, antagonistas trpm8; composicion farmaceutica; y su uso en el tratamiento de la migraña, dolor agudo, inflamatorio o neuropatico, entre otros |
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