ANTICUERPO MONOCLONAL ANTI-RECEPTOR A DE INTERLEUCINA 17 (IL-17RA) O FRAGMENTO DE UNION A ANTIGENO DEL MISMO; POLINUCLEOTIDO QUE LO CODIFICA; METODO DE PREPARACION; Y METODO PARA TRATAR UN TRASTORNO INFLUIDO POR LA ACTIVACION DE IL-17RA

The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or mor...

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Hauptverfasser: FITZPATRICK, DAVID, MEHLIN, CHRISTOPHER, SMOTHERS, JAMES F., LIM, AI CHING, PESCHON, JACQUES, TOCKER, JOEL
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creator FITZPATRICK, DAVID
MEHLIN, CHRISTOPHER
SMOTHERS, JAMES F.
LIM, AI CHING
PESCHON, JACQUES
TOCKER, JOEL
description The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title ANTICUERPO MONOCLONAL ANTI-RECEPTOR A DE INTERLEUCINA 17 (IL-17RA) O FRAGMENTO DE UNION A ANTIGENO DEL MISMO; POLINUCLEOTIDO QUE LO CODIFICA; METODO DE PREPARACION; Y METODO PARA TRATAR UN TRASTORNO INFLUIDO POR LA ACTIVACION DE IL-17RA
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