VERFAHREN ZUR HERSTELLUNG VON 2-BROM-ALPHA-ERGOKRYPTIN

The invention relates to a novel process for the preparation of 2-bromo- alpha -ergocryptine and its acid addition salt by brominating alpha -ergocryptine in such a way that the bromination is carried out at room temperature by using a dimethylsulphoxide-hydrogen bromide mixture containing no more 0...

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Bibliographische Detailangaben
Hauptverfasser:	KEVE, TIBOR, MEGYERI, GABOR, GALAMBOS, JANOS, TRISCHLER, FERENC, STEFKO, BELA, BOGSCH, ERIK, KOVACS, LAJOS
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a novel process for the preparation of 2-bromo- alpha -ergocryptine and its acid addition salt by brominating alpha -ergocryptine in such a way that the bromination is carried out at room temperature by using a dimethylsulphoxide-hydrogen bromide mixture containing no more 0.02% of water and, if desired, converting the thus-obtained 2-bromo- alpha -ergocryptine to an acid addition salt in a known manner.