VERFAHREN ZUR HERSTELLUNG VON CLAVIN-MUTTERKORNALKALOIDEN
The invention relates to a new microbiological process for the preparation of clavine alkaloids of the general formula (I), (I) wherein R stands for hydroxymethyl or methyl group, by cultivation of a Claviceps fusiformis strain in liquid submerged culture medium containing sources of carbon, nitroge...
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| creator | VIDA, ZSUZSANNA TRINN, MARIA KORDIK, GABRIELLA UDVARDY NAGY, EVA (-CSEREY PECHANY) ZSOKA, ERZSEBET (-SOMKUTI) |
| description | The invention relates to a new microbiological process for the preparation of clavine alkaloids of the general formula (I), (I) wherein R stands for hydroxymethyl or methyl group, by cultivation of a Claviceps fusiformis strain in liquid submerged culture medium containing sources of carbon, nitrogen, mineral salts and optionally other additives, under aerobic conditions, in which a Claviceps fusiformis variant strain deposited under No. 00211 is used as alkaloid-producing strain. The invention further relates to a biologically pure culture of the Claviceps fusiformis variant strain No. 00211 obtained in a process in which a Claviceps fusiformis strain No. 00164 is grown in a solid culture medium containing sources of carbon, nitrogen, mineral salts and agar as well as an additive promoting the formation of cytochrome P-450, followed by the selective isolation of the new strain No. 00211. |
| format | Patent |
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The invention further relates to a biologically pure culture of the Claviceps fusiformis variant strain No. 00211 obtained in a process in which a Claviceps fusiformis strain No. 00164 is grown in a solid culture medium containing sources of carbon, nitrogen, mineral salts and agar as well as an additive promoting the formation of cytochrome P-450, followed by the selective isolation of the new strain No. 00211.</description><edition>4</edition><language>ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1988</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19880331&DB=EPODOC&CC=CH&NR=664758A5$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19880331&DB=EPODOC&CC=CH&NR=664758A5$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VIDA, ZSUZSANNA</creatorcontrib><creatorcontrib>TRINN, MARIA</creatorcontrib><creatorcontrib>KORDIK, GABRIELLA</creatorcontrib><creatorcontrib>UDVARDY NAGY, EVA (-CSEREY PECHANY)</creatorcontrib><creatorcontrib>ZSOKA, ERZSEBET (-SOMKUTI)</creatorcontrib><title>VERFAHREN ZUR HERSTELLUNG VON CLAVIN-MUTTERKORNALKALOIDEN</title><description>The invention relates to a new microbiological process for the preparation of clavine alkaloids of the general formula (I), (I) wherein R stands for hydroxymethyl or methyl group, by cultivation of a Claviceps fusiformis strain in liquid submerged culture medium containing sources of carbon, nitrogen, mineral salts and optionally other additives, under aerobic conditions, in which a Claviceps fusiformis variant strain deposited under No. 00211 is used as alkaloid-producing strain. The invention further relates to a biologically pure culture of the Claviceps fusiformis variant strain No. 00211 obtained in a process in which a Claviceps fusiformis strain No. 00164 is grown in a solid culture medium containing sources of carbon, nitrogen, mineral salts and agar as well as an additive promoting the formation of cytochrome P-450, followed by the selective isolation of the new strain No. 00211.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1988</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAMcw1yc_QIcvVTiAoNUvBwDQoOcfXxCfVzVwjz91Nw9nEM8_TT9Q0NCXEN8vYP8nP08Xb08fd0cfXjYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzh5mZibmphaOpsaEVQAANZgonQ</recordid><startdate>19880331</startdate><enddate>19880331</enddate><creator>VIDA, ZSUZSANNA</creator><creator>TRINN, MARIA</creator><creator>KORDIK, GABRIELLA</creator><creator>UDVARDY NAGY, EVA (-CSEREY PECHANY)</creator><creator>ZSOKA, ERZSEBET (-SOMKUTI)</creator><scope>EVB</scope></search><sort><creationdate>19880331</creationdate><title>VERFAHREN ZUR HERSTELLUNG VON CLAVIN-MUTTERKORNALKALOIDEN</title><author>VIDA, ZSUZSANNA ; TRINN, MARIA ; KORDIK, GABRIELLA ; UDVARDY NAGY, EVA (-CSEREY PECHANY) ; ZSOKA, ERZSEBET (-SOMKUTI)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CH664758A53</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1988</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>VIDA, ZSUZSANNA</creatorcontrib><creatorcontrib>TRINN, MARIA</creatorcontrib><creatorcontrib>KORDIK, GABRIELLA</creatorcontrib><creatorcontrib>UDVARDY NAGY, EVA (-CSEREY PECHANY)</creatorcontrib><creatorcontrib>ZSOKA, ERZSEBET (-SOMKUTI)</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>VIDA, ZSUZSANNA</au><au>TRINN, MARIA</au><au>KORDIK, GABRIELLA</au><au>UDVARDY NAGY, EVA (-CSEREY PECHANY)</au><au>ZSOKA, ERZSEBET (-SOMKUTI)</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>VERFAHREN ZUR HERSTELLUNG VON CLAVIN-MUTTERKORNALKALOIDEN</title><date>1988-03-31</date><risdate>1988</risdate><abstract>The invention relates to a new microbiological process for the preparation of clavine alkaloids of the general formula (I), (I) wherein R stands for hydroxymethyl or methyl group, by cultivation of a Claviceps fusiformis strain in liquid submerged culture medium containing sources of carbon, nitrogen, mineral salts and optionally other additives, under aerobic conditions, in which a Claviceps fusiformis variant strain deposited under No. 00211 is used as alkaloid-producing strain. The invention further relates to a biologically pure culture of the Claviceps fusiformis variant strain No. 00211 obtained in a process in which a Claviceps fusiformis strain No. 00164 is grown in a solid culture medium containing sources of carbon, nitrogen, mineral salts and agar as well as an additive promoting the formation of cytochrome P-450, followed by the selective isolation of the new strain No. 00211.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | VERFAHREN ZUR HERSTELLUNG VON CLAVIN-MUTTERKORNALKALOIDEN |
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