DOSIERUNGSEINHEIT ZUR GLEICHZEITIGEN VERABREICHUNG VON WIRKSTOFFEN UND DIE PERKUTANE RESORPTION VERSTAERKENDEN MITTELN

A dosage form that coadministers a drug and a percutaneous absorption enhancer to a defined area of the skin. The dosage form comprises a body that contains supplies of drug and enhancer and has a basal surface that contacts the area of skin and transmits the drug and enhancer to the area for absorp...

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Bibliographische Detailangaben
Hauptverfasser: CAMPBELL, PATRICIA S, CHANDRASEKARAN, SANTOSH K
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:A dosage form that coadministers a drug and a percutaneous absorption enhancer to a defined area of the skin. The dosage form comprises a body that contains supplies of drug and enhancer and has a basal surface that contacts the area of skin and transmits the drug and enhancer to the area for absorption thereby. The drug is provided to the basal surface at a rate at least as great as the rate at which the skin is able to absorb the drug whereas the enhancer is via a rate controlling means at a substantially constant rate that increases the permeability of the treated area of skin to the drug to a level at which the drug is absorbed at a therapeutically effective rate.