BENZYLALKOHOLDERIVATE, IHRE HERSTELLUNG UND SIE ENTHALTENDE PHARMAZEUTISCHE PRAEPARATE

A benzylalcohol derivative of the formula: (I) wherein R is hydroxy, benzyloxy, alkoxy of one to 4 carbon atoms or halogen, and Ring A is monomethoxyphenyl, dimethoxyphenyl, trimethoxyphenyl or 3,4-methylenedioxyphenyl is prepared by reducing a compound of the formula: wherein R' is benzyloxy,...

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Hauptverfasser: NOGUCHI, KATSUYUKI, IWAI, HAJIME, IKEZAKI, MUNEYOSHI, INAMASU, MASANORI
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creator NOGUCHI, KATSUYUKI
IWAI, HAJIME
IKEZAKI, MUNEYOSHI
INAMASU, MASANORI
description A benzylalcohol derivative of the formula: (I) wherein R is hydroxy, benzyloxy, alkoxy of one to 4 carbon atoms or halogen, and Ring A is monomethoxyphenyl, dimethoxyphenyl, trimethoxyphenyl or 3,4-methylenedioxyphenyl is prepared by reducing a compound of the formula: wherein R' is benzyloxy, alkoxy of one to 4 carbon atoms or halogen, and Ring A is the same as defined above, and when R' is benzyloxy, if required, further subjecting the product to catalytic hydrogenation. The compounds (I) and pharmaceutically acceptable acid addition salts thereof are used as anti-diabetic agents.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BENZYLALKOHOLDERIVATE, IHRE HERSTELLUNG UND SIE ENTHALTENDE PHARMAZEUTISCHE PRAEPARATE
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