(A) Cmpds. (I) and (III):- R' = lower alkyl R2 = H or Me R3 = lower Oalkyl or together = -OCH2O-IA - X = H; IB X = double bond. (B) Sa
(A) Cmpds. (I) and (III):- R' = lower alkyl R2 = H or Me R3 = lower Oalkyl or together = -OCH2O-IA - X = H; IB - X = double bond. (B) Salts (II) of (I). (I) and (II) Analgesics. Dose 100-500 mg. (III) Intermediates for (I) and (II) Racemic cis-1-methyl-3-(3,4-methylenedioxy-phenyl)-4-piperidyl-...
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creator | LINDENMANN,ADOLF,DR SUEESS,RUDOLF,DR |
description | (A) Cmpds. (I) and (III):- R' = lower alkyl R2 = H or Me R3 = lower Oalkyl or together = -OCH2O-IA - X = H; IB - X = double bond. (B) Salts (II) of (I). (I) and (II) Analgesics. Dose 100-500 mg. (III) Intermediates for (I) and (II) Racemic cis-1-methyl-3-(3,4-methylenedioxy-phenyl)-4-piperidyl-amine (6.0 g.), 2 N HCl (35 ml.), and 35% HCHO (5 g.) were stirred 30 mins. at 20 deg., heated 30 mins. at 100 deg., evapd., and recryst. from MeOH, giving the racemic-naphthyridine-HCl, m.p. 304 deg. |
format | Patent |
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(III) Intermediates for (I) and (II) Racemic cis-1-methyl-3-(3,4-methylenedioxy-phenyl)-4-piperidyl-amine (6.0 g.), 2 N HCl (35 ml.), and 35% HCHO (5 g.) were stirred 30 mins. at 20 deg., heated 30 mins. at 100 deg., evapd., and recryst. from MeOH, giving the racemic-naphthyridine-HCl, m.p. 304 deg.</description><edition>1</edition><language>eng ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1971</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19710831&DB=EPODOC&CC=CH&NR=511871A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19710831&DB=EPODOC&CC=CH&NR=511871A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LINDENMANN,ADOLF,DR</creatorcontrib><creatorcontrib>SUEESS,RUDOLF,DR</creatorcontrib><title>(A) Cmpds. 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(III) Intermediates for (I) and (II) Racemic cis-1-methyl-3-(3,4-methylenedioxy-phenyl)-4-piperidyl-amine (6.0 g.), 2 N HCl (35 ml.), and 35% HCHO (5 g.) were stirred 30 mins. at 20 deg., heated 30 mins. at 100 deg., evapd., and recryst. from MeOH, giving the racemic-naphthyridine-HCl, m.p. 304 deg.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1971</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZGjTcNRUcM4tSCnWU9Dw1FRIzEsB0p6emla6CkHqCrYKOfnlqUUKiTnZlTkKQUZAAQ-F_CIF31SFIGO4rD9EGihekp-eWpIBFLJV0PV39jDy1_V0VNBViADps1bwdAKzUvJLk3JSFZLy81KAljppKgQn8jCwpiXmFKfyQmluBjk31xBnD93Ugvz41OKCxOTUvNSSeGcPU0NDC3NDR2OCCgAwaz3m</recordid><startdate>19710831</startdate><enddate>19710831</enddate><creator>LINDENMANN,ADOLF,DR</creator><creator>SUEESS,RUDOLF,DR</creator><scope>EVB</scope></search><sort><creationdate>19710831</creationdate><title>(A) Cmpds. (I) and (III):- R' = lower alkyl R2 = H or Me R3 = lower Oalkyl or together = -OCH2O-IA - X = H; IB X = double bond. (B) Sa</title><author>LINDENMANN,ADOLF,DR ; SUEESS,RUDOLF,DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CH511871A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; ger</language><creationdate>1971</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>LINDENMANN,ADOLF,DR</creatorcontrib><creatorcontrib>SUEESS,RUDOLF,DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LINDENMANN,ADOLF,DR</au><au>SUEESS,RUDOLF,DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>(A) Cmpds. (I) and (III):- R' = lower alkyl R2 = H or Me R3 = lower Oalkyl or together = -OCH2O-IA - X = H; IB X = double bond. (B) Sa</title><date>1971-08-31</date><risdate>1971</risdate><abstract>(A) Cmpds. (I) and (III):- R' = lower alkyl R2 = H or Me R3 = lower Oalkyl or together = -OCH2O-IA - X = H; IB - X = double bond. (B) Salts (II) of (I). (I) and (II) Analgesics. Dose 100-500 mg. (III) Intermediates for (I) and (II) Racemic cis-1-methyl-3-(3,4-methylenedioxy-phenyl)-4-piperidyl-amine (6.0 g.), 2 N HCl (35 ml.), and 35% HCHO (5 g.) were stirred 30 mins. at 20 deg., heated 30 mins. at 100 deg., evapd., and recryst. from MeOH, giving the racemic-naphthyridine-HCl, m.p. 304 deg.</abstract><edition>1</edition><oa>free_for_read</oa></addata></record> |
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language | eng ; ger |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
title | (A) Cmpds. (I) and (III):- R' = lower alkyl R2 = H or Me R3 = lower Oalkyl or together = -OCH2O-IA - X = H; IB X = double bond. (B) Sa |
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