Verfahren zur Herstellung neuer substituierter 7-Heterocyclo-7,8-dihydro-6-methoxy-6,14-endo-(ätheno oder äthano)-codide und -morphide
1,243,838. Analgesics. AMERICAN CYANAMID CO. 8 Nov., 1968 [12 Jan., 1968], No. 53147/68. Heading A5B. [Also in Division C2] Analgesic compositions in the form of injectable solutions or unit dosages for oral administration, comprise compounds of formula their non-toxic acid addition salts and their...
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| creator | JOHNSTON BROWN,JOHN ALLIS HARDY,ROBERT |
| description | 1,243,838. Analgesics. AMERICAN CYANAMID CO. 8 Nov., 1968 [12 Jan., 1968], No. 53147/68. Heading A5B. [Also in Division C2] Analgesic compositions in the form of injectable solutions or unit dosages for oral administration, comprise compounds of formula their non-toxic acid addition salts and their alkali metal salts (when R 1 =H) wherein R 1 is H or C 1-4 alkyl or C 2-5 alkanoyl, R 2 is H, CN, propargyl, C 1-4 alkyl (possibly Ph-substituted), C 2-6 alkenyl or cycloalkylmethyl (C 4-7 ), R 3 is H or Me, Y is -CH:CH- or -CH 2 CH 2 -, Q is a group of formula where R 4 is H or C 1-7 alkyl, is -NR 5 N=, -ON= or -N=C(NH 2 )N=, and R 5 is H, C 1-4 alkyl, Ph (possibly halo, CF 3 or C 1-4 alkyl or alkoxy substituted), pyridyl, quinolyl, benzothiazolyl, dimethylpyrimidyl or dimethyl-s-triazinyl. These compounds may be adminstered in combination with salicylates such as aspirin. |
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Analgesics. AMERICAN CYANAMID CO. 8 Nov., 1968 [12 Jan., 1968], No. 53147/68. Heading A5B. [Also in Division C2] Analgesic compositions in the form of injectable solutions or unit dosages for oral administration, comprise compounds of formula their non-toxic acid addition salts and their alkali metal salts (when R 1 =H) wherein R 1 is H or C 1-4 alkyl or C 2-5 alkanoyl, R 2 is H, CN, propargyl, C 1-4 alkyl (possibly Ph-substituted), C 2-6 alkenyl or cycloalkylmethyl (C 4-7 ), R 3 is H or Me, Y is -CH:CH- or -CH 2 CH 2 -, Q is a group of formula where R 4 is H or C 1-7 alkyl, is -NR 5 N=, -ON= or -N=C(NH 2 )N=, and R 5 is H, C 1-4 alkyl, Ph (possibly halo, CF 3 or C 1-4 alkyl or alkoxy substituted), pyridyl, quinolyl, benzothiazolyl, dimethylpyrimidyl or dimethyl-s-triazinyl. 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Analgesics. AMERICAN CYANAMID CO. 8 Nov., 1968 [12 Jan., 1968], No. 53147/68. Heading A5B. [Also in Division C2] Analgesic compositions in the form of injectable solutions or unit dosages for oral administration, comprise compounds of formula their non-toxic acid addition salts and their alkali metal salts (when R 1 =H) wherein R 1 is H or C 1-4 alkyl or C 2-5 alkanoyl, R 2 is H, CN, propargyl, C 1-4 alkyl (possibly Ph-substituted), C 2-6 alkenyl or cycloalkylmethyl (C 4-7 ), R 3 is H or Me, Y is -CH:CH- or -CH 2 CH 2 -, Q is a group of formula where R 4 is H or C 1-7 alkyl, is -NR 5 N=, -ON= or -N=C(NH 2 )N=, and R 5 is H, C 1-4 alkyl, Ph (possibly halo, CF 3 or C 1-4 alkyl or alkoxy substituted), pyridyl, quinolyl, benzothiazolyl, dimethylpyrimidyl or dimethyl-s-triazinyl. These compounds may be adminstered in combination with salicylates such as aspirin.</abstract><edition>1</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | Verfahren zur Herstellung neuer substituierter 7-Heterocyclo-7,8-dihydro-6-methoxy-6,14-endo-(ätheno oder äthano)-codide und -morphide |
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