ANTIBODY OR FRAGMENT THEREOF BINDING SPECIFICALLY TO MERTK, AND ANTI-TUMOR AGENT
A problem addressed by the present invention is to provide an anti-MerTK antibody that has a tumor-suppressing effect and does not tend to cause ocular toxicity.?The present invention provides an antibody or a fragment thereof that binds specifically to MerTK, in which the amino acid sequences of he...
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| creator | KAMBAYASHI, HIROAKI TAKESUE, AKI TOYOURA, MASAYOSHI INOUE, TOSHIKAZU SAWADA, ATSUSHI |
| description | A problem addressed by the present invention is to provide an anti-MerTK antibody that has a tumor-suppressing effect and does not tend to cause ocular toxicity.?The present invention provides an antibody or a fragment thereof that binds specifically to MerTK, in which the amino acid sequences of heavy chain and light chain CDRs 1 to 3 satisfy predetermined requirements.
Un problème abordé par la présente invention est de fournir un anticorps anti-MerTK qui a un effet de suppression de tumeur et qui n'a pas tendance à provoquer une toxicité oculaire.?La présente invention concerne un anticorps ou un fragment de celui-ci qui se lie spécifiquement à MerTK, dans lequel les séquences d'acides aminés de CDR de chaîne lourde et de chaîne légère 1 à 3 satisfont des exigences prédéterminées. |
| format | Patent |
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Un problème abordé par la présente invention est de fournir un anticorps anti-MerTK qui a un effet de suppression de tumeur et qui n'a pas tendance à provoquer une toxicité oculaire.?La présente invention concerne un anticorps ou un fragment de celui-ci qui se lie spécifiquement à MerTK, dans lequel les séquences d'acides aminés de CDR de chaîne lourde et de chaîne légère 1 à 3 satisfont des exigences prédéterminées.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAhw9AvxdPJ3iVTwD1JwC3J093X1C1EI8XANcvV3U3Dy9HPx9HNXCA5wdfZ083R29PGJVAjxV_B1DQrx1lFw9HNRAOnXDQn1BWp3dAfq5WFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8c6OxkbGxpZmFo6GxkQoAQD69S5U</recordid><startdate>20230420</startdate><enddate>20230420</enddate><creator>KAMBAYASHI, HIROAKI</creator><creator>TAKESUE, AKI</creator><creator>TOYOURA, MASAYOSHI</creator><creator>INOUE, TOSHIKAZU</creator><creator>SAWADA, ATSUSHI</creator><scope>EVB</scope></search><sort><creationdate>20230420</creationdate><title>ANTIBODY OR FRAGMENT THEREOF BINDING SPECIFICALLY TO MERTK, AND ANTI-TUMOR AGENT</title><author>KAMBAYASHI, HIROAKI ; TAKESUE, AKI ; TOYOURA, MASAYOSHI ; INOUE, TOSHIKAZU ; SAWADA, ATSUSHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3233968A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><toplevel>online_resources</toplevel><creatorcontrib>KAMBAYASHI, HIROAKI</creatorcontrib><creatorcontrib>TAKESUE, AKI</creatorcontrib><creatorcontrib>TOYOURA, MASAYOSHI</creatorcontrib><creatorcontrib>INOUE, TOSHIKAZU</creatorcontrib><creatorcontrib>SAWADA, ATSUSHI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KAMBAYASHI, HIROAKI</au><au>TAKESUE, AKI</au><au>TOYOURA, MASAYOSHI</au><au>INOUE, TOSHIKAZU</au><au>SAWADA, ATSUSHI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIBODY OR FRAGMENT THEREOF BINDING SPECIFICALLY TO MERTK, AND ANTI-TUMOR AGENT</title><date>2023-04-20</date><risdate>2023</risdate><abstract>A problem addressed by the present invention is to provide an anti-MerTK antibody that has a tumor-suppressing effect and does not tend to cause ocular toxicity.?The present invention provides an antibody or a fragment thereof that binds specifically to MerTK, in which the amino acid sequences of heavy chain and light chain CDRs 1 to 3 satisfy predetermined requirements.
Un problème abordé par la présente invention est de fournir un anticorps anti-MerTK qui a un effet de suppression de tumeur et qui n'a pas tendance à provoquer une toxicité oculaire.?La présente invention concerne un anticorps ou un fragment de celui-ci qui se lie spécifiquement à MerTK, dans lequel les séquences d'acides aminés de CDR de chaîne lourde et de chaîne légère 1 à 3 satisfont des exigences prédéterminées.</abstract><oa>free_for_read</oa></addata></record> |
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| title | ANTIBODY OR FRAGMENT THEREOF BINDING SPECIFICALLY TO MERTK, AND ANTI-TUMOR AGENT |
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