CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS

The present disclosure relates to heterobifunctional molecules, referred to as cytotoxicity targeting chimeras (CyTaCs) or antibody recruiting molecules (ARMs) that are able to simultaneously bind a target cell-surface protein as well as an exogenous antibody protein. The present disclosure also rel...

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Bibliographische Detailangaben

Hauptverfasser:	SENDER, MATTHEW ROBERT, DODSON, JASON W, LEACH, CRAIG, LI, YUEHU, KNAPP-REED, BETH A, CHEN, PEILING, TURUNEN, BRANDON, YE, GUOSEN, MARINO JR., JOSEPH PAUL, ZHANG, CUNYU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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