SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS

This disclosure is drawn to pyridine derivatives, compositions thereof: and associated methods, useful for inhibition of SARM1 activity and/or for treating or preventing neurological disorders. SARM1 activation can cause a rapid reduction in NAD+ levels in injured axons, which then undergo degenerat...

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Hauptverfasser:	TEGLEY, CHRISTOPHER MICHAEL, REYNOLDS, CHARLES HOWARD, BROWN, SEAN POMEROY, ZHU, LIUSHENG, TASKER, ANDREW STEWART, GRICE, CHERYL A, KOLLURI, RAO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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