MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER

The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer. La présente invention concerne une polythérapie utilisant un agent de liai...

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Hauptverfasser: BLUM, JORDAN, GARRIDO CASTRO, PATRICIA, FERESHTEH, MARK, PAULMANN, CLAUDIA, HIGGS, BRANDON, MUIK, ALEXANDER, SPIRES, VANESSA, BREIJ, ESTHER CORNELIA WILHELMINA, DE KREUK, BART-JAN, BAJAJ, GAURAV, GUELEN, LARS, HIBBERT, RICHARD, FU, YALI, LABRIJN, ARAN FRANK, SAHIN, UGUR, FELLERMEIER-KOPF, SINA, NEIJSSEN, JOST, BECKMANN, KARSTEN, KUZMANOV, IVAN, ADAMS, HOMER III, NIEWOOD, MICHELLE, SCHUURMAN, JANINE, GIESEKE, FRIEDERIKE
Format: Patent
Sprache:eng ; fre
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