CHECKPOINT INHIBITORS CONJUGATED TO IL-2, AND USES THEREOF
The present disclosure relates to modified anti-PD-1 polypeptides, pharmaceutical compositions comprising modified anti-PD-1 polypeptides, methods of making anti-PD-1 polypeptides, and methods of using the modified anti-PD-1 polypeptides for treatment of diseases. In one aspect, the disclosure relat...
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| creator | ALVAREZ SANCHEZ, RUBEN PATTABIRAMAN, VIJAYA RAGHAVAN AREVALO-RUIZ, MATILDE MULLER, MAGALI CARRALOT, JEAN-PHILIPPE KREFT, BERTOLT |
| description | The present disclosure relates to modified anti-PD-1 polypeptides, pharmaceutical compositions comprising modified anti-PD-1 polypeptides, methods of making anti-PD-1 polypeptides, and methods of using the modified anti-PD-1 polypeptides for treatment of diseases. In one aspect, the disclosure relates to methods of treating cancer in a subject using the modified anti-PD-1 polypeptides.
La présente divulgation concerne des polypeptides anti-PD-1 modifiés, des compositions pharmaceutiques comprenant les polypeptides anti-PD-1 modifiés, des procédés de préparation de polypeptides anti-PD-1 modifiés, ainsi que des méthodes d'utilisation des polypeptides anti-PD-1 modifiés pour le traitement de maladies. Dans un aspect, l'invention concerne des méthodes de traitement du cancer chez un sujet à l'aide des polypeptides anti-PD-1 modifiés. |
| format | Patent |
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La présente divulgation concerne des polypeptides anti-PD-1 modifiés, des compositions pharmaceutiques comprenant les polypeptides anti-PD-1 modifiés, des procédés de préparation de polypeptides anti-PD-1 modifiés, ainsi que des méthodes d'utilisation des polypeptides anti-PD-1 modifiés pour le traitement de maladies. Dans un aspect, l'invention concerne des méthodes de traitement du cancer chez un sujet à l'aide des polypeptides anti-PD-1 modifiés.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230112&DB=EPODOC&CC=CA&NR=3222358A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230112&DB=EPODOC&CC=CA&NR=3222358A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ALVAREZ SANCHEZ, RUBEN</creatorcontrib><creatorcontrib>PATTABIRAMAN, VIJAYA RAGHAVAN</creatorcontrib><creatorcontrib>AREVALO-RUIZ, MATILDE</creatorcontrib><creatorcontrib>MULLER, MAGALI</creatorcontrib><creatorcontrib>CARRALOT, JEAN-PHILIPPE</creatorcontrib><creatorcontrib>KREFT, BERTOLT</creatorcontrib><title>CHECKPOINT INHIBITORS CONJUGATED TO IL-2, AND USES THEREOF</title><description>The present disclosure relates to modified anti-PD-1 polypeptides, pharmaceutical compositions comprising modified anti-PD-1 polypeptides, methods of making anti-PD-1 polypeptides, and methods of using the modified anti-PD-1 polypeptides for treatment of diseases. In one aspect, the disclosure relates to methods of treating cancer in a subject using the modified anti-PD-1 polypeptides.
La présente divulgation concerne des polypeptides anti-PD-1 modifiés, des compositions pharmaceutiques comprenant les polypeptides anti-PD-1 modifiés, des procédés de préparation de polypeptides anti-PD-1 modifiés, ainsi que des méthodes d'utilisation des polypeptides anti-PD-1 modifiés pour le traitement de maladies. Dans un aspect, l'invention concerne des méthodes de traitement du cancer chez un sujet à l'aide des polypeptides anti-PD-1 modifiés.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLBy9nB19g7w9_QLUfD08_B08gzxDwpWcPb38wp1dwxxdVEI8Vfw9NE10lFw9HNRCA12DVYI8XANcvV342FgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8c6OxkZGRsamFo6GxkQoAQBCuCgj</recordid><startdate>20230112</startdate><enddate>20230112</enddate><creator>ALVAREZ SANCHEZ, RUBEN</creator><creator>PATTABIRAMAN, VIJAYA RAGHAVAN</creator><creator>AREVALO-RUIZ, MATILDE</creator><creator>MULLER, MAGALI</creator><creator>CARRALOT, JEAN-PHILIPPE</creator><creator>KREFT, BERTOLT</creator><scope>EVB</scope></search><sort><creationdate>20230112</creationdate><title>CHECKPOINT INHIBITORS CONJUGATED TO IL-2, AND USES THEREOF</title><author>ALVAREZ SANCHEZ, RUBEN ; PATTABIRAMAN, VIJAYA RAGHAVAN ; AREVALO-RUIZ, MATILDE ; MULLER, MAGALI ; CARRALOT, JEAN-PHILIPPE ; KREFT, BERTOLT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3222358A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>ALVAREZ SANCHEZ, RUBEN</creatorcontrib><creatorcontrib>PATTABIRAMAN, VIJAYA RAGHAVAN</creatorcontrib><creatorcontrib>AREVALO-RUIZ, MATILDE</creatorcontrib><creatorcontrib>MULLER, MAGALI</creatorcontrib><creatorcontrib>CARRALOT, JEAN-PHILIPPE</creatorcontrib><creatorcontrib>KREFT, BERTOLT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ALVAREZ SANCHEZ, RUBEN</au><au>PATTABIRAMAN, VIJAYA RAGHAVAN</au><au>AREVALO-RUIZ, MATILDE</au><au>MULLER, MAGALI</au><au>CARRALOT, JEAN-PHILIPPE</au><au>KREFT, BERTOLT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CHECKPOINT INHIBITORS CONJUGATED TO IL-2, AND USES THEREOF</title><date>2023-01-12</date><risdate>2023</risdate><abstract>The present disclosure relates to modified anti-PD-1 polypeptides, pharmaceutical compositions comprising modified anti-PD-1 polypeptides, methods of making anti-PD-1 polypeptides, and methods of using the modified anti-PD-1 polypeptides for treatment of diseases. In one aspect, the disclosure relates to methods of treating cancer in a subject using the modified anti-PD-1 polypeptides.
La présente divulgation concerne des polypeptides anti-PD-1 modifiés, des compositions pharmaceutiques comprenant les polypeptides anti-PD-1 modifiés, des procédés de préparation de polypeptides anti-PD-1 modifiés, ainsi que des méthodes d'utilisation des polypeptides anti-PD-1 modifiés pour le traitement de maladies. Dans un aspect, l'invention concerne des méthodes de traitement du cancer chez un sujet à l'aide des polypeptides anti-PD-1 modifiés.</abstract><oa>free_for_read</oa></addata></record> |
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| title | CHECKPOINT INHIBITORS CONJUGATED TO IL-2, AND USES THEREOF |
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