COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS
Macromolecule compositions and related methods that effect targeted delivery of therapeutic agents to effector targets in a desired cell, tissue and/or organ of interest while minimizing or avoiding undesirable delivery to other cells, tissues or organs are provided. Compositions and methods related...
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| creator | NICOD, CHARLOTTE MARIE KOHAR, VIVEK CARLSON, SCOTT MOORE BLOM, DANIEL ROTHSCHILDS, ADRIENNE MARIE MARSHALL, STEPHEN KAHVEJIAN, AVAK AFEYAN, NOUBAR BOGHOS ECHELARD, YANN PAUL GUY REGIS PLUGIS, NICHOLAS MCCARTNEY AFEYAN, RAFFI |
| description | Macromolecule compositions and related methods that effect targeted delivery of therapeutic agents to effector targets in a desired cell, tissue and/or organ of interest while minimizing or avoiding undesirable delivery to other cells, tissues or organs are provided. Compositions and methods related to macromolecules, such as an ANDbody?, that include an effector target binding domain specific for an effector target, and an address binding domain specific for an address target are described.
La présente invention concerne des compositions macromoléculaires et des procédés associés effectuant une administration ciblée d'agents thérapeutiques à des cibles effectrices dans une cellule, un tissu et/ou un organe d'intérêt souhaité tout en minimisant ou en évitant une administration indésirable à d'autres cellules, tissus ou organes. L'invention concerne également des compositions et des procédés relatifs à des macromolécules, telles qu'un ANDbody?, comportant un domaine de liaison de cible effectrice spécifique d'une cible effectrice, et un domaine de liaison d'adresse spécifique d'une cible d'adresse. |
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La présente invention concerne des compositions macromoléculaires et des procédés associés effectuant une administration ciblée d'agents thérapeutiques à des cibles effectrices dans une cellule, un tissu et/ou un organe d'intérêt souhaité tout en minimisant ou en évitant une administration indésirable à d'autres cellules, tissus ou organes. L'invention concerne également des compositions et des procédés relatifs à des macromolécules, telles qu'un ANDbody?, comportant un domaine de liaison de cible effectrice spécifique d'une cible effectrice, et un domaine de liaison d'adresse spécifique d'une cible d'adresse.</description><language>eng ; fre</language><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221215&DB=EPODOC&CC=CA&NR=3221544A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221215&DB=EPODOC&CC=CA&NR=3221544A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NICOD, CHARLOTTE MARIE</creatorcontrib><creatorcontrib>KOHAR, VIVEK</creatorcontrib><creatorcontrib>CARLSON, SCOTT MOORE</creatorcontrib><creatorcontrib>BLOM, DANIEL</creatorcontrib><creatorcontrib>ROTHSCHILDS, ADRIENNE MARIE</creatorcontrib><creatorcontrib>MARSHALL, STEPHEN</creatorcontrib><creatorcontrib>KAHVEJIAN, AVAK</creatorcontrib><creatorcontrib>AFEYAN, NOUBAR BOGHOS</creatorcontrib><creatorcontrib>ECHELARD, YANN PAUL GUY REGIS</creatorcontrib><creatorcontrib>PLUGIS, NICHOLAS MCCARTNEY</creatorcontrib><creatorcontrib>AFEYAN, RAFFI</creatorcontrib><title>COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS</title><description>Macromolecule compositions and related methods that effect targeted delivery of therapeutic agents to effector targets in a desired cell, tissue and/or organ of interest while minimizing or avoiding undesirable delivery to other cells, tissues or organs are provided. Compositions and methods related to macromolecules, such as an ANDbody?, that include an effector target binding domain specific for an effector target, and an address binding domain specific for an address target are described.
La présente invention concerne des compositions macromoléculaires et des procédés associés effectuant une administration ciblée d'agents thérapeutiques à des cibles effectrices dans une cellule, un tissu et/ou un organe d'intérêt souhaité tout en minimisant ou en évitant une administration indésirable à d'autres cellules, tissus ou organes. L'invention concerne également des compositions et des procédés relatifs à des macromolécules, telles qu'un ANDbody?, comportant un domaine de liaison de cible effectrice spécifique d'une cible effectrice, et un domaine de liaison d'adresse spécifique d'une cible d'adresse.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBx9vcN8A_2DPH09wtWcPRzUfB1DfHwdwlWcPMPUghxDHJ3DXF1UXBx9fEMcw2KVPB3UwjxcA1yDHANDfF0VnB0d_ULCeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHOjsZGRoamJiaOhsZEKAEAFVArWQ</recordid><startdate>20221215</startdate><enddate>20221215</enddate><creator>NICOD, CHARLOTTE MARIE</creator><creator>KOHAR, VIVEK</creator><creator>CARLSON, SCOTT MOORE</creator><creator>BLOM, DANIEL</creator><creator>ROTHSCHILDS, ADRIENNE MARIE</creator><creator>MARSHALL, STEPHEN</creator><creator>KAHVEJIAN, AVAK</creator><creator>AFEYAN, NOUBAR BOGHOS</creator><creator>ECHELARD, YANN PAUL GUY REGIS</creator><creator>PLUGIS, NICHOLAS MCCARTNEY</creator><creator>AFEYAN, RAFFI</creator><scope>EVB</scope></search><sort><creationdate>20221215</creationdate><title>COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS</title><author>NICOD, CHARLOTTE MARIE ; KOHAR, VIVEK ; CARLSON, SCOTT MOORE ; BLOM, DANIEL ; ROTHSCHILDS, ADRIENNE MARIE ; MARSHALL, STEPHEN ; KAHVEJIAN, AVAK ; AFEYAN, NOUBAR BOGHOS ; ECHELARD, YANN PAUL GUY REGIS ; PLUGIS, NICHOLAS MCCARTNEY ; AFEYAN, RAFFI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3221544A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><toplevel>online_resources</toplevel><creatorcontrib>NICOD, CHARLOTTE MARIE</creatorcontrib><creatorcontrib>KOHAR, VIVEK</creatorcontrib><creatorcontrib>CARLSON, SCOTT MOORE</creatorcontrib><creatorcontrib>BLOM, DANIEL</creatorcontrib><creatorcontrib>ROTHSCHILDS, ADRIENNE MARIE</creatorcontrib><creatorcontrib>MARSHALL, STEPHEN</creatorcontrib><creatorcontrib>KAHVEJIAN, AVAK</creatorcontrib><creatorcontrib>AFEYAN, NOUBAR BOGHOS</creatorcontrib><creatorcontrib>ECHELARD, YANN PAUL GUY REGIS</creatorcontrib><creatorcontrib>PLUGIS, NICHOLAS MCCARTNEY</creatorcontrib><creatorcontrib>AFEYAN, RAFFI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NICOD, CHARLOTTE MARIE</au><au>KOHAR, VIVEK</au><au>CARLSON, SCOTT MOORE</au><au>BLOM, DANIEL</au><au>ROTHSCHILDS, ADRIENNE MARIE</au><au>MARSHALL, STEPHEN</au><au>KAHVEJIAN, AVAK</au><au>AFEYAN, NOUBAR BOGHOS</au><au>ECHELARD, YANN PAUL GUY REGIS</au><au>PLUGIS, NICHOLAS MCCARTNEY</au><au>AFEYAN, RAFFI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS</title><date>2022-12-15</date><risdate>2022</risdate><abstract>Macromolecule compositions and related methods that effect targeted delivery of therapeutic agents to effector targets in a desired cell, tissue and/or organ of interest while minimizing or avoiding undesirable delivery to other cells, tissues or organs are provided. Compositions and methods related to macromolecules, such as an ANDbody?, that include an effector target binding domain specific for an effector target, and an address binding domain specific for an address target are described.
La présente invention concerne des compositions macromoléculaires et des procédés associés effectuant une administration ciblée d'agents thérapeutiques à des cibles effectrices dans une cellule, un tissu et/ou un organe d'intérêt souhaité tout en minimisant ou en évitant une administration indésirable à d'autres cellules, tissus ou organes. L'invention concerne également des compositions et des procédés relatifs à des macromolécules, telles qu'un ANDbody?, comportant un domaine de liaison de cible effectrice spécifique d'une cible effectrice, et un domaine de liaison d'adresse spécifique d'une cible d'adresse.</abstract><oa>free_for_read</oa></addata></record> |
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| title | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS |
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