PHARMACEUTICAL COMPOSITIONS CONTAINING PSILOCYBIN FOR IMPROVED DISSOLUTION AND RAPID ONSET BY TARGETED STOMACH AND MUCOSAL RELEASE
Phamiaceutical compositions are provided containing psilocybin, which are designed for rapid dissolution properties and immediate or rapid release. The compositions are designed for targeted release by way of: (1) stomach release; or (2) mucosal release. The compositions can be used as pre-formulati...
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creator | WONG, NICHOLAS JO LIE CID, MARIA VANESA FERNANDEZ |
description | Phamiaceutical compositions are provided containing psilocybin, which are designed for rapid dissolution properties and immediate or rapid release. The compositions are designed for targeted release by way of: (1) stomach release; or (2) mucosal release. The compositions can be used as pre-formulations for further tableting, encapsulation, or formulating into a sublingual dosage form for oral use, designed for rapid therapeutic onset. Particularly, the compositions overcome unfavourable fommlati on characteristics of psilocybin that cause drug release variability and problems for formulating into finished dosage forms. More particularly, psilocybin is fommlated in a manner to overcome drug release variability thereby providing unifomi potency and desirable bioavailability characteristics. The compositions may be used for inducing therapeutically beneficial behaviour change in subjects with a variety of psychiatric conditions. |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | PHARMACEUTICAL COMPOSITIONS CONTAINING PSILOCYBIN FOR IMPROVED DISSOLUTION AND RAPID ONSET BY TARGETED STOMACH AND MUCOSAL RELEASE |
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