MARKERS OF PREDICTION OF RESPONSE TO CAR T CELL THERAPY

This invention relates to in vitro methods for predicting the response of a subject to autologous chimeric antigen receptor T-cell (CAR T-cell) therapy, the methods comprising determining the methylation status of one or more cytosines in CpG sites of CAR T-cells. There are also disclosed means and...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	ESTELLER BADOSA, MANEL, VILLANUEVA LEGARDA, LOREA, GARCIA PRIETO, CARLOS ANTONIO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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