ANTI-TRPV6 MONOCLONAL ANTIBODY AND APPLICATION THEREOF
A segment of characteristic polypeptide antigen of a TRPV6 protein is selected to immunize mice and then screening is performed to obtain hybridoma cell lines 12CT 9.5.1, 16CT 18.1.1.2 and 16CT 4.1.1.2. The series of cells can secrete monoclonal antibodies against TRPV6 and can specifically recogniz...
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| creator | WANG, WEI HUANG, BAOHUA ROBERT WANG, ZHONGBO TAN, WEI |
| description | A segment of characteristic polypeptide antigen of a TRPV6 protein is selected to immunize mice and then screening is performed to obtain hybridoma cell lines 12CT 9.5.1, 16CT 18.1.1.2 and 16CT 4.1.1.2. The series of cells can secrete monoclonal antibodies against TRPV6 and can specifically recognize the TRPV6 protein and tumor tissue. The series of antibodies can measure the level of TRPV6 in cells in an artificial or automated manner by means of immunohistochemistry (IHC), enzyme-linked immunosorbent assay (ELISA), immunofluorescence (IF), chemiluminescence (CLA), immunoturbidimetric (TIA), or western blot, are thus used in a method for diagnosing tumor tissue, and relate to the field of biological detection.
Un segment d'antigène polypeptidique caractéristique d'une protéine TRPV6 est sélectionné pour immuniser des souris, puis un criblage est effectué pour obtenir des lignées cellulaires d'hybridomes 12CT 9.5.1, 16CT 18.1.1.2 et 16CT 4.1.1.2. La série de cellules peut sécréter des anticorps monoclonaux contre TRPV6 et peut reconnaître de manière spécifique la protéine TRPV6 et le tissu tumoral. La série d'anticorps peut mesurer le niveau de TRPV6 dans des cellules de manière artificielle ou automatisée par immunohistochimie (IHC), dosage immunoenzymatique lié à des enzymes (ELISA), immunofluorescence (IF), chimioluminescence (CLA), immunoturbidimétrie (TIA) ou par western blot, sont ainsi utilisés dans une méthode diagnostique de tissu tumoral, et se rapportent au domaine de la détection biologique. |
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Un segment d'antigène polypeptidique caractéristique d'une protéine TRPV6 est sélectionné pour immuniser des souris, puis un criblage est effectué pour obtenir des lignées cellulaires d'hybridomes 12CT 9.5.1, 16CT 18.1.1.2 et 16CT 4.1.1.2. La série de cellules peut sécréter des anticorps monoclonaux contre TRPV6 et peut reconnaître de manière spécifique la protéine TRPV6 et le tissu tumoral. La série d'anticorps peut mesurer le niveau de TRPV6 dans des cellules de manière artificielle ou automatisée par immunohistochimie (IHC), dosage immunoenzymatique lié à des enzymes (ELISA), immunofluorescence (IF), chimioluminescence (CLA), immunoturbidimétrie (TIA) ou par western blot, sont ainsi utilisés dans une méthode diagnostique de tissu tumoral, et se rapportent au domaine de la détection biologique.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220721&DB=EPODOC&CC=CA&NR=3206472A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220721&DB=EPODOC&CC=CA&NR=3206472A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WANG, WEI</creatorcontrib><creatorcontrib>HUANG, BAOHUA ROBERT</creatorcontrib><creatorcontrib>WANG, ZHONGBO</creatorcontrib><creatorcontrib>TAN, WEI</creatorcontrib><title>ANTI-TRPV6 MONOCLONAL ANTIBODY AND APPLICATION THEREOF</title><description>A segment of characteristic polypeptide antigen of a TRPV6 protein is selected to immunize mice and then screening is performed to obtain hybridoma cell lines 12CT 9.5.1, 16CT 18.1.1.2 and 16CT 4.1.1.2. The series of cells can secrete monoclonal antibodies against TRPV6 and can specifically recognize the TRPV6 protein and tumor tissue. The series of antibodies can measure the level of TRPV6 in cells in an artificial or automated manner by means of immunohistochemistry (IHC), enzyme-linked immunosorbent assay (ELISA), immunofluorescence (IF), chemiluminescence (CLA), immunoturbidimetric (TIA), or western blot, are thus used in a method for diagnosing tumor tissue, and relate to the field of biological detection.
Un segment d'antigène polypeptidique caractéristique d'une protéine TRPV6 est sélectionné pour immuniser des souris, puis un criblage est effectué pour obtenir des lignées cellulaires d'hybridomes 12CT 9.5.1, 16CT 18.1.1.2 et 16CT 4.1.1.2. La série de cellules peut sécréter des anticorps monoclonaux contre TRPV6 et peut reconnaître de manière spécifique la protéine TRPV6 et le tissu tumoral. La série d'anticorps peut mesurer le niveau de TRPV6 dans des cellules de manière artificielle ou automatisée par immunohistochimie (IHC), dosage immunoenzymatique lié à des enzymes (ELISA), immunofluorescence (IF), chimioluminescence (CLA), immunoturbidimétrie (TIA) ou par western blot, sont ainsi utilisés dans une méthode diagnostique de tissu tumoral, et se rapportent au domaine de la détection biologique.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDBz9Avx1A0JCggzU_D19_N39vH3c_RRAIk6-btEAhkuCo4BAT6ezo4hnv5-CiEerkGu_m48DKxpiTnFqbxQmptBwc01xNlDN7UgPz61uCAxOTUvtSTe2dHYyMDMxNzI0dCYCCUAyzwnbg</recordid><startdate>20220721</startdate><enddate>20220721</enddate><creator>WANG, WEI</creator><creator>HUANG, BAOHUA ROBERT</creator><creator>WANG, ZHONGBO</creator><creator>TAN, WEI</creator><scope>EVB</scope></search><sort><creationdate>20220721</creationdate><title>ANTI-TRPV6 MONOCLONAL ANTIBODY AND APPLICATION THEREOF</title><author>WANG, WEI ; HUANG, BAOHUA ROBERT ; WANG, ZHONGBO ; TAN, WEI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3206472A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG, WEI</creatorcontrib><creatorcontrib>HUANG, BAOHUA ROBERT</creatorcontrib><creatorcontrib>WANG, ZHONGBO</creatorcontrib><creatorcontrib>TAN, WEI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG, WEI</au><au>HUANG, BAOHUA ROBERT</au><au>WANG, ZHONGBO</au><au>TAN, WEI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTI-TRPV6 MONOCLONAL ANTIBODY AND APPLICATION THEREOF</title><date>2022-07-21</date><risdate>2022</risdate><abstract>A segment of characteristic polypeptide antigen of a TRPV6 protein is selected to immunize mice and then screening is performed to obtain hybridoma cell lines 12CT 9.5.1, 16CT 18.1.1.2 and 16CT 4.1.1.2. The series of cells can secrete monoclonal antibodies against TRPV6 and can specifically recognize the TRPV6 protein and tumor tissue. The series of antibodies can measure the level of TRPV6 in cells in an artificial or automated manner by means of immunohistochemistry (IHC), enzyme-linked immunosorbent assay (ELISA), immunofluorescence (IF), chemiluminescence (CLA), immunoturbidimetric (TIA), or western blot, are thus used in a method for diagnosing tumor tissue, and relate to the field of biological detection.
Un segment d'antigène polypeptidique caractéristique d'une protéine TRPV6 est sélectionné pour immuniser des souris, puis un criblage est effectué pour obtenir des lignées cellulaires d'hybridomes 12CT 9.5.1, 16CT 18.1.1.2 et 16CT 4.1.1.2. La série de cellules peut sécréter des anticorps monoclonaux contre TRPV6 et peut reconnaître de manière spécifique la protéine TRPV6 et le tissu tumoral. La série d'anticorps peut mesurer le niveau de TRPV6 dans des cellules de manière artificielle ou automatisée par immunohistochimie (IHC), dosage immunoenzymatique lié à des enzymes (ELISA), immunofluorescence (IF), chimioluminescence (CLA), immunoturbidimétrie (TIA) ou par western blot, sont ainsi utilisés dans une méthode diagnostique de tissu tumoral, et se rapportent au domaine de la détection biologique.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | ANTI-TRPV6 MONOCLONAL ANTIBODY AND APPLICATION THEREOF |
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