LIPID NANOPARTICLES COMPRISING MANNOSE OR USES THEREOF

The present invention relates to lipid nanoparticles comprising mannose or a use thereof. The lipid nanoparticles according to an embodiment are specific for liver tissues and/or LSEC, have excellent biological affinity, and can deliver gene therapeutic agents, etc. at high efficiency, thus finding...

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Hauptverfasser: KIM, MINJEONG, LEE, HYUKJIN, JEONG, MICHAELA
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creator KIM, MINJEONG
LEE, HYUKJIN
JEONG, MICHAELA
description The present invention relates to lipid nanoparticles comprising mannose or a use thereof. The lipid nanoparticles according to an embodiment are specific for liver tissues and/or LSEC, have excellent biological affinity, and can deliver gene therapeutic agents, etc. at high efficiency, thus finding advantageous applications in the relevant technical fields such as lipid nanoparticle-mediated gene therapy, etc. La présente invention concerne des nanoparticules lipidiques comprenant du mannose ou leur utilisation. Les nanoparticules lipidiques selon un mode de réalisation sont spécifiques des tissus du foie et/ou de la LSEC, ont une excellente affinité biologique, et peuvent délivrer des agents de thérapie génique, etc., à un rendement élevé, ce qui permet de trouver des applications avantageuses dans les domaines techniques pertinents tels que la thérapie génique médiée par des nanoparticules lipidiques, etc.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title LIPID NANOPARTICLES COMPRISING MANNOSE OR USES THEREOF
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