CRYSTALLINE RET INHIBITOR

Provided herein is a crystalline form of selpercatinib useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders, and methods of making this crystalline form. La présente invention concerne une forme cristalli...

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Hauptverfasser: MERRITT, JEREMY MILES, BHARDWAJ, RAJNI MIGLANI, KERR, MARK STEVEN, KJELL, DOUGLAS PATTON, VISWANATH, SHEKHAR KRISHNA, SELBO, JON GORDON
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creator MERRITT, JEREMY MILES
BHARDWAJ, RAJNI MIGLANI
KERR, MARK STEVEN
KJELL, DOUGLAS PATTON
VISWANATH, SHEKHAR KRISHNA
SELBO, JON GORDON
description Provided herein is a crystalline form of selpercatinib useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders, and methods of making this crystalline form. La présente invention concerne une forme cristalline de selpercatinib utile dans le traitement et la prévention de maladies qui peuvent être traitées avec un inhibiteur de kinase RET, y compris des maladies et des troubles associés à RET, et des procédés de production de cette forme cristalline.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CRYSTALLINE RET INHIBITOR
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