POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS

Extracellular protein degraders and compositions are provided that have a potent asialoglycoprotein receptor (ASGPR) Binding Ligand bound to an Extracellular Protein Targeting Ligand for the selective degradation of the Target Extracellular Protein, for example immunoglobulin in vivo to treat disord...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SPROTT, KEVIN TYLER, SAULNIER, MARK GEORGE, KARRA, SRINIVASA, RAY, SOUMYA, CHEN, JESSE JINGYANG, WILES, JASON ALLAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES SUGARS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	SPROTT, KEVIN TYLER SAULNIER, MARK GEORGE KARRA, SRINIVASA RAY, SOUMYA CHEN, JESSE JINGYANG WILES, JASON ALLAN
description	Extracellular protein degraders and compositions are provided that have a potent asialoglycoprotein receptor (ASGPR) Binding Ligand bound to an Extracellular Protein Targeting Ligand for the selective degradation of the Target Extracellular Protein, for example immunoglobulin in vivo to treat disorders mediated by the extracellular protein.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA3174145A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA3174145A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA3174145A13</originalsourceid><addsrcrecordid>eNqNjEsKwjAUALNxIeod3gW6CK24TpM0DTTvhXygu1IkrkQL9f6YhQdwNTAMc2Szp6QxgYjGh6a3qCwakOQ8ZVQRBgqQRg1KmyCUSJYQaADrXEYyE_V5shhBoAKqXQAf6rCqMzs81udeLj-eGAw6ybEp23sp-7bey6t8Filafut4dxW8_SP5Aq_QMPo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS</title><source>esp@cenet</source><creator>SPROTT, KEVIN TYLER ; SAULNIER, MARK GEORGE ; KARRA, SRINIVASA ; RAY, SOUMYA ; CHEN, JESSE JINGYANG ; WILES, JASON ALLAN</creator><creatorcontrib>SPROTT, KEVIN TYLER ; SAULNIER, MARK GEORGE ; KARRA, SRINIVASA ; RAY, SOUMYA ; CHEN, JESSE JINGYANG ; WILES, JASON ALLAN</creatorcontrib><description>Extracellular protein degraders and compositions are provided that have a potent asialoglycoprotein receptor (ASGPR) Binding Ligand bound to an Extracellular Protein Targeting Ligand for the selective degradation of the Target Extracellular Protein, for example immunoglobulin in vivo to treat disorders mediated by the extracellular protein.</description><language>eng ; fre</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PEPTIDES ; SUGARS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221110&DB=EPODOC&CC=CA&NR=3174145A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221110&DB=EPODOC&CC=CA&NR=3174145A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SPROTT, KEVIN TYLER</creatorcontrib><creatorcontrib>SAULNIER, MARK GEORGE</creatorcontrib><creatorcontrib>KARRA, SRINIVASA</creatorcontrib><creatorcontrib>RAY, SOUMYA</creatorcontrib><creatorcontrib>CHEN, JESSE JINGYANG</creatorcontrib><creatorcontrib>WILES, JASON ALLAN</creatorcontrib><title>POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS</title><description>Extracellular protein degraders and compositions are provided that have a potent asialoglycoprotein receptor (ASGPR) Binding Ligand bound to an Extracellular Protein Targeting Ligand for the selective degradation of the Target Extracellular Protein, for example immunoglobulin in vivo to treat disorders mediated by the extracellular protein.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEsKwjAUALNxIeod3gW6CK24TpM0DTTvhXygu1IkrkQL9f6YhQdwNTAMc2Szp6QxgYjGh6a3qCwakOQ8ZVQRBgqQRg1KmyCUSJYQaADrXEYyE_V5shhBoAKqXQAf6rCqMzs81udeLj-eGAw6ybEp23sp-7bey6t8Filafut4dxW8_SP5Aq_QMPo</recordid><startdate>20221110</startdate><enddate>20221110</enddate><creator>SPROTT, KEVIN TYLER</creator><creator>SAULNIER, MARK GEORGE</creator><creator>KARRA, SRINIVASA</creator><creator>RAY, SOUMYA</creator><creator>CHEN, JESSE JINGYANG</creator><creator>WILES, JASON ALLAN</creator><scope>EVB</scope></search><sort><creationdate>20221110</creationdate><title>POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS</title><author>SPROTT, KEVIN TYLER ; SAULNIER, MARK GEORGE ; KARRA, SRINIVASA ; RAY, SOUMYA ; CHEN, JESSE JINGYANG ; WILES, JASON ALLAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3174145A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>SPROTT, KEVIN TYLER</creatorcontrib><creatorcontrib>SAULNIER, MARK GEORGE</creatorcontrib><creatorcontrib>KARRA, SRINIVASA</creatorcontrib><creatorcontrib>RAY, SOUMYA</creatorcontrib><creatorcontrib>CHEN, JESSE JINGYANG</creatorcontrib><creatorcontrib>WILES, JASON ALLAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SPROTT, KEVIN TYLER</au><au>SAULNIER, MARK GEORGE</au><au>KARRA, SRINIVASA</au><au>RAY, SOUMYA</au><au>CHEN, JESSE JINGYANG</au><au>WILES, JASON ALLAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS</title><date>2022-11-10</date><risdate>2022</risdate><abstract>Extracellular protein degraders and compositions are provided that have a potent asialoglycoprotein receptor (ASGPR) Binding Ligand bound to an Extracellular Protein Targeting Ligand for the selective degradation of the Target Extracellular Protein, for example immunoglobulin in vivo to treat disorders mediated by the extracellular protein.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng ; fre
recordid	cdi_epo_espacenet_CA3174145A1
source	esp@cenet
subjects	CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES SUGARS
title	POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T03%3A59%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SPROTT,%20KEVIN%20TYLER&rft.date=2022-11-10&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA3174145A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true