HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE
[Problem] To provide a peptide, etc., capable of passing through the blood-brain barrier (BBB) by binding to a human transferrin receptor (hTfR). [Solution] A peptide, etc., having the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) or an amino acid sequen...
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| creator | INABA, SHINNOSUKE TAKUWA, MASATOSHI SAWAI, NAOKI MASUYA, KEIICHI YODEN, EIJI TAKAHASHI, KENICHI FUJIYAMA, SAKI BASHIRUDDIN, NASIR KATO NAKAMURA, NAOKO OHUCHI, MASAKI EHARA, TAKERU HASHIMOTO, HIDEHIKO |
| description | [Problem] To provide a peptide, etc., capable of passing through the blood-brain barrier (BBB) by binding to a human transferrin receptor (hTfR). [Solution] A peptide, etc., having the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) or an amino acid sequence having substitutions, deletions, additions, and/or insertions of 1 to 10 amino acid residues (inclusive) in the amino acid sequence shown in SEQ ID NO: 1.
Le problème décrit par la présente invention est de fournir un peptide, etc, pouvant traverser la barrière hémato-encéphalique (BBB) par liaison à un récepteur de la transferrine humaine (hTfR). La solution selon l'invention porte sur un peptide, etc, ayant la séquence d'acides aminés présentée dans SEQ ID NO : 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) ou une séquence d'acides aminés ayant des substitutions, des délétions, des additions et/ou des insertions de 1 à 10 résidus d'acides aminés (inclus) dans la séquence d'acides aminés présentée dans SEQ ID NO : 1. |
| format | Patent |
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Le problème décrit par la présente invention est de fournir un peptide, etc, pouvant traverser la barrière hémato-encéphalique (BBB) par liaison à un récepteur de la transferrine humaine (hTfR). La solution selon l'invention porte sur un peptide, etc, ayant la séquence d'acides aminés présentée dans SEQ ID NO : 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) ou une séquence d'acides aminés ayant des substitutions, des délétions, des additions et/ou des insertions de 1 à 10 résidus d'acides aminés (inclus) dans la séquence d'acides aminés présentée dans SEQ ID NO : 1.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210826&DB=EPODOC&CC=CA&NR=3171988A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25566,76549</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210826&DB=EPODOC&CC=CA&NR=3171988A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>INABA, SHINNOSUKE</creatorcontrib><creatorcontrib>TAKUWA, MASATOSHI</creatorcontrib><creatorcontrib>SAWAI, NAOKI</creatorcontrib><creatorcontrib>MASUYA, KEIICHI</creatorcontrib><creatorcontrib>YODEN, EIJI</creatorcontrib><creatorcontrib>TAKAHASHI, KENICHI</creatorcontrib><creatorcontrib>FUJIYAMA, SAKI</creatorcontrib><creatorcontrib>BASHIRUDDIN, NASIR KATO</creatorcontrib><creatorcontrib>NAKAMURA, NAOKO</creatorcontrib><creatorcontrib>OHUCHI, MASAKI</creatorcontrib><creatorcontrib>EHARA, TAKERU</creatorcontrib><creatorcontrib>HASHIMOTO, HIDEHIKO</creatorcontrib><title>HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE</title><description>[Problem] To provide a peptide, etc., capable of passing through the blood-brain barrier (BBB) by binding to a human transferrin receptor (hTfR). [Solution] A peptide, etc., having the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) or an amino acid sequence having substitutions, deletions, additions, and/or insertions of 1 to 10 amino acid residues (inclusive) in the amino acid sequence shown in SEQ ID NO: 1.
Le problème décrit par la présente invention est de fournir un peptide, etc, pouvant traverser la barrière hémato-encéphalique (BBB) par liaison à un récepteur de la transferrine humaine (hTfR). La solution selon l'invention porte sur un peptide, etc, ayant la séquence d'acides aminés présentée dans SEQ ID NO : 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) ou une séquence d'acides aminés ayant des substitutions, des délétions, des additions et/ou des insertions de 1 à 10 résidus d'acides aminés (inclus) dans la séquence d'acides aminés présentée dans SEQ ID NO : 1.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDyCPV19FMICXL0C3ZzDQry9FMIcnV2DQjxD1Jw8vRz8fRzVwgAcj1dXHkYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSbyzo7GhuaGlhYWjoTERSgAYaCRS</recordid><startdate>20210826</startdate><enddate>20210826</enddate><creator>INABA, SHINNOSUKE</creator><creator>TAKUWA, MASATOSHI</creator><creator>SAWAI, NAOKI</creator><creator>MASUYA, KEIICHI</creator><creator>YODEN, EIJI</creator><creator>TAKAHASHI, KENICHI</creator><creator>FUJIYAMA, SAKI</creator><creator>BASHIRUDDIN, NASIR KATO</creator><creator>NAKAMURA, NAOKO</creator><creator>OHUCHI, MASAKI</creator><creator>EHARA, TAKERU</creator><creator>HASHIMOTO, HIDEHIKO</creator><scope>EVB</scope></search><sort><creationdate>20210826</creationdate><title>HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE</title><author>INABA, SHINNOSUKE ; TAKUWA, MASATOSHI ; SAWAI, NAOKI ; MASUYA, KEIICHI ; YODEN, EIJI ; TAKAHASHI, KENICHI ; FUJIYAMA, SAKI ; BASHIRUDDIN, NASIR KATO ; NAKAMURA, NAOKO ; OHUCHI, MASAKI ; EHARA, TAKERU ; HASHIMOTO, HIDEHIKO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3171988A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>INABA, SHINNOSUKE</creatorcontrib><creatorcontrib>TAKUWA, MASATOSHI</creatorcontrib><creatorcontrib>SAWAI, NAOKI</creatorcontrib><creatorcontrib>MASUYA, KEIICHI</creatorcontrib><creatorcontrib>YODEN, EIJI</creatorcontrib><creatorcontrib>TAKAHASHI, KENICHI</creatorcontrib><creatorcontrib>FUJIYAMA, SAKI</creatorcontrib><creatorcontrib>BASHIRUDDIN, NASIR KATO</creatorcontrib><creatorcontrib>NAKAMURA, NAOKO</creatorcontrib><creatorcontrib>OHUCHI, MASAKI</creatorcontrib><creatorcontrib>EHARA, TAKERU</creatorcontrib><creatorcontrib>HASHIMOTO, HIDEHIKO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>INABA, SHINNOSUKE</au><au>TAKUWA, MASATOSHI</au><au>SAWAI, NAOKI</au><au>MASUYA, KEIICHI</au><au>YODEN, EIJI</au><au>TAKAHASHI, KENICHI</au><au>FUJIYAMA, SAKI</au><au>BASHIRUDDIN, NASIR KATO</au><au>NAKAMURA, NAOKO</au><au>OHUCHI, MASAKI</au><au>EHARA, TAKERU</au><au>HASHIMOTO, HIDEHIKO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE</title><date>2021-08-26</date><risdate>2021</risdate><abstract>[Problem] To provide a peptide, etc., capable of passing through the blood-brain barrier (BBB) by binding to a human transferrin receptor (hTfR). [Solution] A peptide, etc., having the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) or an amino acid sequence having substitutions, deletions, additions, and/or insertions of 1 to 10 amino acid residues (inclusive) in the amino acid sequence shown in SEQ ID NO: 1.
Le problème décrit par la présente invention est de fournir un peptide, etc, pouvant traverser la barrière hémato-encéphalique (BBB) par liaison à un récepteur de la transferrine humaine (hTfR). La solution selon l'invention porte sur un peptide, etc, ayant la séquence d'acides aminés présentée dans SEQ ID NO : 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys) ou une séquence d'acides aminés ayant des substitutions, des délétions, des additions et/ou des insertions de 1 à 10 résidus d'acides aminés (inclus) dans la séquence d'acides aminés présentée dans SEQ ID NO : 1.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE |
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