ALPHA-HYDROXYLATED FATTY ACID METABOLITES, MEDICAL USES OF SAME AND USE AS BIOMARKERS

Described are fatty acids with one or more unsaturations, having an odd hydrocarbon chain, the fatty acids having the chemical structure of the therapeutically active metabolites of even-chain mono- or polyunsaturated alpha-hydroxylated fatty acids. Also described are compositions comprising said fatty acids, medical uses thereof, and the use thereof as indicators of the efficacy of and/or response to the treatment of a patient with the even-chain mono- or polyunsaturated alpha-hydroxylated fatty acids from which they are derived. L'invention concerne des acides gras à une ou plusieurs insaturations, de chaîne hydrocarbonée impaire, ces acides gras ayant la structure chimique des métabolites thérapeutiquement actifs d'acides gras alpha-hydroxylés mono ou polyinsaturés de chaîne paire. L'invention concerne, en outre, les compositions qui comprennent ces acides gras, leurs utilisations médicales, ainsi que leur utilisation comme indicateurs de l'efficacité et/ou de la réponse au traitement d'un patient avec les acides gras alpha-hydroxylés mono ou polyinsaturés de chaîne paire desquels ils sont dérivés.