BIOMARKERS AND USES THEREOF FOR DIAGNOSING THE SILENT PHASE OF ALZHEIMER'S DISEASE

The present invention relates to a molecular signature of the silent phase of Alzheimer's disease; and to methods using the same, for diagnosing a silent stage of Alzheimer's disease in a subject, stratifying a silent phase of Alzheimer's disease in a subject into different grades of...

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Hauptverfasser: BILLOIR, BAPTISTE, BRAUDEAU, JEROME, SOUCHET, BENOIT, MICHAIL, ALKEOS
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creator BILLOIR, BAPTISTE
BRAUDEAU, JEROME
SOUCHET, BENOIT
MICHAIL, ALKEOS
description The present invention relates to a molecular signature of the silent phase of Alzheimer's disease; and to methods using the same, for diagnosing a silent stage of Alzheimer's disease in a subject, stratifying a silent phase of Alzheimer's disease in a subject into different grades of the silent phase, prognosticating the progress of a silent phase of Alzheimer's disease in a subject, and determining a personalized course of treatment in a subject affected with a silent phase of Alzheimer's disease. It also relates to a computer system comprising a machine learning algorithm trained for diagnosing a silent phase of Alzheimer's disease in a subject. La présente invention concerne une signature moléculaire de la phase silencieuse de la maladie d'Alzheimer; et des procédés faisant appel à celle-ci pour diagnostiquer un stade silencieux de la maladie d'Alzheimer chez un sujet, stratifier une phase silencieuse de la maladie d'Alzheimer chez un sujet en différents degrés de la phase silencieuse, pronostiquer l'évolution d'une phase silencieuse de la maladie d'Alzheimer chez un sujet, et déterminer un déroulement personnalisé du traitement chez un sujet atteint d'une phase silencieuse de la maladie d'Alzheimer. L'invention concerne également un système informatique comprenant un algorithme d'apprentissage automatique entraîné pour diagnostiquer une phase silencieuse de la maladie d'Alzheimer chez un sujet.
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language eng ; fre
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title BIOMARKERS AND USES THEREOF FOR DIAGNOSING THE SILENT PHASE OF ALZHEIMER'S DISEASE
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