OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF

Among other things, the present disclosure provides C9orf72 oligonucleotides, compositions, and methods thereof. In some embodiments, the present disclosure provides methods for treating C9orf72-associated conditions, disorders or diseases, such as amyotrophic lateral sclerosis and frontotemporal de...

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Hauptverfasser: VARGEESE, CHANDRA, ANDREUCCI, AMY JADA, LIU, YUANJING, ZHONG, ZHONG, IWAMOTO, NAOKI, MOHAPATRA, SUSOVAN
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creator VARGEESE, CHANDRA
ANDREUCCI, AMY JADA
LIU, YUANJING
ZHONG, ZHONG
IWAMOTO, NAOKI
MOHAPATRA, SUSOVAN
description Among other things, the present disclosure provides C9orf72 oligonucleotides, compositions, and methods thereof. In some embodiments, the present disclosure provides methods for treating C9orf72-associated conditions, disorders or diseases, such as amyotrophic lateral sclerosis and frontotemporal dementia. Entre autres, la présente invention concerne des oligonucléotides C9orf72, des compositions et des procédés associés. Dans certains modes de réalisation, la présente invention concerne des méthodes de traitement d'états, de troubles ou de maladies associés à C9orf72, tels que la sclérose latérale amyotrophique et la démence frontotemporale.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF
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