IL-38-SPECIFIC ANTIBODIES
This invention relates to antibodies specific for human interleukin-38 (IL-38), including isolated antibodies, or antigen-binding fragments thereof. The antibodies, or antigen-binding fragments thereof, described here partially or fully block, inhibit, or neutralize a biological activity of IL 38. M...
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creator | HARMAN, BEN NIKITIN, PAVEL A ROBINSON, MATTHEW K LUNDGREN, KAREN DOWLING, JOHN P |
description | This invention relates to antibodies specific for human interleukin-38 (IL-38), including isolated antibodies, or antigen-binding fragments thereof. The antibodies, or antigen-binding fragments thereof, described here partially or fully block, inhibit, or neutralize a biological activity of IL 38. Methods described here relate to inhibiting tumor growth or metastasis in an individual afflicted by tumor growth and/or metastasis.
La présente invention concerne des anticorps spécifiques de l'interleukine 38 humaine (IL-38) comprenant des anticorps isolés ou leurs fragments de liaison à l'antigène. Les anticorps ou leurs fragments de liaison à l'antigène susmentionnés bloquent, inhibent ou neutralisent, partiellement ou totalement, une activité biologique de l'IL-38. Les procédés susmentionnés concernent l'inhibition de la croissance tumorale ou de la métastase chez un individu présentant une croissance tumorale et/ou une métastase. |
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La présente invention concerne des anticorps spécifiques de l'interleukine 38 humaine (IL-38) comprenant des anticorps isolés ou leurs fragments de liaison à l'antigène. Les anticorps ou leurs fragments de liaison à l'antigène susmentionnés bloquent, inhibent ou neutralisent, partiellement ou totalement, une activité biologique de l'IL-38. Les procédés susmentionnés concernent l'inhibition de la croissance tumorale ou de la métastase chez un individu présentant une croissance tumorale et/ou une métastase.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210204&DB=EPODOC&CC=CA&NR=3149198A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210204&DB=EPODOC&CC=CA&NR=3149198A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HARMAN, BEN</creatorcontrib><creatorcontrib>NIKITIN, PAVEL A</creatorcontrib><creatorcontrib>ROBINSON, MATTHEW K</creatorcontrib><creatorcontrib>LUNDGREN, KAREN</creatorcontrib><creatorcontrib>DOWLING, JOHN P</creatorcontrib><title>IL-38-SPECIFIC ANTIBODIES</title><description>This invention relates to antibodies specific for human interleukin-38 (IL-38), including isolated antibodies, or antigen-binding fragments thereof. The antibodies, or antigen-binding fragments thereof, described here partially or fully block, inhibit, or neutralize a biological activity of IL 38. Methods described here relate to inhibiting tumor growth or metastasis in an individual afflicted by tumor growth and/or metastasis.
La présente invention concerne des anticorps spécifiques de l'interleukine 38 humaine (IL-38) comprenant des anticorps isolés ou leurs fragments de liaison à l'antigène. Les anticorps ou leurs fragments de liaison à l'antigène susmentionnés bloquent, inhibent ou neutralisent, partiellement ou totalement, une activité biologique de l'IL-38. Les procédés susmentionnés concernent l'inhibition de la croissance tumorale ou de la métastase chez un individu présentant une croissance tumorale et/ou une métastase.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJD09NE1ttANDnB19nTzdFZw9AvxdPJ38XQN5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8c6OxoYmloaWFo6GxkQoAQCwXB8u</recordid><startdate>20210204</startdate><enddate>20210204</enddate><creator>HARMAN, BEN</creator><creator>NIKITIN, PAVEL A</creator><creator>ROBINSON, MATTHEW K</creator><creator>LUNDGREN, KAREN</creator><creator>DOWLING, JOHN P</creator><scope>EVB</scope></search><sort><creationdate>20210204</creationdate><title>IL-38-SPECIFIC ANTIBODIES</title><author>HARMAN, BEN ; NIKITIN, PAVEL A ; ROBINSON, MATTHEW K ; LUNDGREN, KAREN ; DOWLING, JOHN P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3149198A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HARMAN, BEN</creatorcontrib><creatorcontrib>NIKITIN, PAVEL A</creatorcontrib><creatorcontrib>ROBINSON, MATTHEW K</creatorcontrib><creatorcontrib>LUNDGREN, KAREN</creatorcontrib><creatorcontrib>DOWLING, JOHN P</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HARMAN, BEN</au><au>NIKITIN, PAVEL A</au><au>ROBINSON, MATTHEW K</au><au>LUNDGREN, KAREN</au><au>DOWLING, JOHN P</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IL-38-SPECIFIC ANTIBODIES</title><date>2021-02-04</date><risdate>2021</risdate><abstract>This invention relates to antibodies specific for human interleukin-38 (IL-38), including isolated antibodies, or antigen-binding fragments thereof. The antibodies, or antigen-binding fragments thereof, described here partially or fully block, inhibit, or neutralize a biological activity of IL 38. Methods described here relate to inhibiting tumor growth or metastasis in an individual afflicted by tumor growth and/or metastasis.
La présente invention concerne des anticorps spécifiques de l'interleukine 38 humaine (IL-38) comprenant des anticorps isolés ou leurs fragments de liaison à l'antigène. Les anticorps ou leurs fragments de liaison à l'antigène susmentionnés bloquent, inhibent ou neutralisent, partiellement ou totalement, une activité biologique de l'IL-38. Les procédés susmentionnés concernent l'inhibition de la croissance tumorale ou de la métastase chez un individu présentant une croissance tumorale et/ou une métastase.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | IL-38-SPECIFIC ANTIBODIES |
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