COMPOSITIONS FOR MAINTAINING OR MODULATING MIXTURES OF ETHER LIPID MOLECULES IN A TISSUE OF A HUMAN SUBJECT

Provided herein is a composition comprising a mixture of ether lipid molecules of Formula (I) as defined herein. The composition is for in vivo maintenance of ether lipids at levels and/or ratios associated with a non-disease state, or wherein the composition is for in vivo modification of ether lip...

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1. Verfasser: MEIKLE, PETER JOHN
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description Provided herein is a composition comprising a mixture of ether lipid molecules of Formula (I) as defined herein. The composition is for in vivo maintenance of ether lipids at levels and/or ratios associated with a non-disease state, or wherein the composition is for in vivo modification of ether lipids towards levels and/or ratios associated with a non-disease state. Also provided herein are methods of assessing subject for metabolic disease or dyslipidemia, comprising measuring relative abundance of one or more ether lipid side chains in a biological sample from a subject, methods of preventing or treating disorders such as metabolic disease or dyslipidemia, or methods of preventing conditions such as obesity and asthma, particularly in infants, involving administering a composition as defined herein. L'invention concerne une composition comprenant un mélange de molécules éther lipidiques représentés par la formule (I) telle que définie dans la description. La composition est destinée au maintien in vivo d'éther lipides à des niveaux et/ou des rapports associés à un état non pathologique, ou la composition est destinée à la modification in vivo d'éther lipides pour atteindre des niveaux et/ou des rapports associés à un état non pathologique. L'invention concerne également des procédés d'évaluation d'un sujet concernant une maladie métabolique ou une dyslipidémie, comprenant l'étape consistant à mesurer l'abondance relative d'une ou de plusieurs chaînes latérales d'éther lipides dans un échantillon biologique issu d'un sujet, des procédés de prévention ou de traitement de troubles tels qu'une pathologie métabolique ou la dyslipidémie, ou des procédés de prévention d'affections tels que l'obésité et l'asthme, en particulier chez les nourrissons, impliquant l'administration d'une composition telle que définie dans la description.
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La composition est destinée au maintien in vivo d'éther lipides à des niveaux et/ou des rapports associés à un état non pathologique, ou la composition est destinée à la modification in vivo d'éther lipides pour atteindre des niveaux et/ou des rapports associés à un état non pathologique. L'invention concerne également des procédés d'évaluation d'un sujet concernant une maladie métabolique ou une dyslipidémie, comprenant l'étape consistant à mesurer l'abondance relative d'une ou de plusieurs chaînes latérales d'éther lipides dans un échantillon biologique issu d'un sujet, des procédés de prévention ou de traitement de troubles tels qu'une pathologie métabolique ou la dyslipidémie, ou des procédés de prévention d'affections tels que l'obésité et l'asthme, en particulier chez les nourrissons, impliquant l'administration d'une composition telle que définie dans la description.</abstract><oa>free_for_read</oa></addata></record>
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subjects FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title COMPOSITIONS FOR MAINTAINING OR MODULATING MIXTURES OF ETHER LIPID MOLECULES IN A TISSUE OF A HUMAN SUBJECT
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