QUINAZOLIN-4-ONE DERIVATIVES USEFUL FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS

Provided herein are compounds of the Formula I: and pharmaceutically acceptable salts, solvates and polymorphs thereof, wherein L, X1, R1, R2, R3, R4, R5 and R6 are as defined herein, for the treatment of BRAF-associated diseases and disorders, including BRAF-associated tumors, including malignant a...

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Hauptverfasser:	BARBOUR, PATRICK MICHAEL, TARLTON, EUGENE, BROWN, KATIE KEATON, KAHN, DEAN RUSSELL, PRIGARO, BRETT JOSEPH, REN, LI, HICKEN, ERIK JAMES, MORENO, DAVID AUSTIN, NEWHOUSE, BRADLEY JON, METCALF, ANDREW TERRANCE, PAJK, SPENCER PHILLIP, LAIRD, ELLEN RUTH, COOK, ADAM WADE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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