5-(THIOPHEN-2-YL)-1H-TETRAZOLE DERIVATIVES AS BCKDK INHIBITORS USEFUL FOR TREATING VARIOUS DISEASES

Described herein are compounds of Formula (I), wherein R1, R2, and R3 are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, diabetes, NASH and heart...

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Bibliographische Detailangaben

Hauptverfasser:	OMOTO, KIYOYUKI, REESE, MATTHEW RICHARD, FILIPSKI, KEVIN JAMES, ZHANG, YUAN, KORMOS, BETHANY LYN, MILLER, RUSSELL ALAN, BHATTACHARYA, SAMIT KUMAR, BUTLER, CHRISTOPHER RYAN, MARTINEZ-ALSINA, LUIS ANGEL, ROTH FLACH, RACHEL JANE, RAYMER, BRIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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