SYNTHESIS OF TRANS-8-CHLORO-5-METHYL- 1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF
The present invention relates to a process to synthesize a compound of formula I, comprising reacting a compound of formula XII with a compound of formula XX (see formula XII)(see formula XX)(see formula XIX)(see formula I) Also disclosed are compounds useful as intermediates in the methods of the i...
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| creator | TRUSSARDI, RENE HOFFMANN-EMERY, FABIENNE PFLEGER, CHRISTOPHE BARTELS, BJOERN GRASSMANN, OLAF ROTHENHAEULSLER, BENNO HARTUNG, THOMAS ADAM, JEAN-MICHEL SCHWITTER, URS RAN, FREDERIC DIODONE, RALPH |
| description | The present invention relates to a process to synthesize a compound of formula I, comprising reacting a compound of formula XII with a compound of formula XX (see formula XII)(see formula XX)(see formula XIX)(see formula I) Also disclosed are compounds useful as intermediates in the methods of the invention.
La présente invention concerne un procédé visant à synthétiser un composé de formule I comprenant une réaction entre un composé de formule XII avec un composé de formule XX (voir formule XII) [voir formule XX] (voir formule XIX) [voir formule I]. Il est également décrit des composés pouvant être utiles comme intermédiaires dans les procédés de linvention. |
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La présente invention concerne un procédé visant à synthétiser un composé de formule I comprenant une réaction entre un composé de formule XII avec un composé de formule XX (voir formule XII) [voir formule XX] (voir formule XIX) [voir formule I]. Il est également décrit des composés pouvant être utiles comme intermédiaires dans les procédés de linvention.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240102&DB=EPODOC&CC=CA&NR=3142754C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240102&DB=EPODOC&CC=CA&NR=3142754C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TRUSSARDI, RENE</creatorcontrib><creatorcontrib>HOFFMANN-EMERY, FABIENNE</creatorcontrib><creatorcontrib>PFLEGER, CHRISTOPHE</creatorcontrib><creatorcontrib>BARTELS, BJOERN</creatorcontrib><creatorcontrib>GRASSMANN, OLAF</creatorcontrib><creatorcontrib>ROTHENHAEULSLER, BENNO</creatorcontrib><creatorcontrib>HARTUNG, THOMAS</creatorcontrib><creatorcontrib>ADAM, JEAN-MICHEL</creatorcontrib><creatorcontrib>SCHWITTER, URS</creatorcontrib><creatorcontrib>RAN, FREDERIC</creatorcontrib><creatorcontrib>DIODONE, RALPH</creatorcontrib><title>SYNTHESIS OF TRANS-8-CHLORO-5-METHYL- 1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF</title><description>The present invention relates to a process to synthesize a compound of formula I, comprising reacting a compound of formula XII with a compound of formula XX (see formula XII)(see formula XX)(see formula XIX)(see formula I) Also disclosed are compounds useful as intermediates in the methods of the invention.
La présente invention concerne un procédé visant à synthétiser un composé de formule I comprenant une réaction entre un composé de formule XII avec un composé de formule XX (voir formule XII) [voir formule XX] (voir formule XIX) [voir formule I]. Il est également décrit des composés pouvant être utiles comme intermédiaires dans les procédés de linvention.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjr0KwjAUhbs4iPoMZlToBfunrjG9JYGYSBKhtyIiEidRQR_Gx7WDu9PhwHc-zjD5eDJBolee2YYFx42HNQiprbNQwRaDJA0sg0MJsx05VSsDOZC2Lc1BkNBWYkv6CFW6hFpJqvthKSFPi7RKs8UGAvZa3nHYoOnsAY-822s0yLipmXDkA9da9b2xbutZ_8ahbcbJ4Hq-veLkl6Nk2mAQEuLzcYqv5_kS7_F9ErzIynxVlaL4T3wB0XRBIg</recordid><startdate>20240102</startdate><enddate>20240102</enddate><creator>TRUSSARDI, RENE</creator><creator>HOFFMANN-EMERY, FABIENNE</creator><creator>PFLEGER, CHRISTOPHE</creator><creator>BARTELS, BJOERN</creator><creator>GRASSMANN, OLAF</creator><creator>ROTHENHAEULSLER, BENNO</creator><creator>HARTUNG, THOMAS</creator><creator>ADAM, JEAN-MICHEL</creator><creator>SCHWITTER, URS</creator><creator>RAN, FREDERIC</creator><creator>DIODONE, RALPH</creator><scope>EVB</scope></search><sort><creationdate>20240102</creationdate><title>SYNTHESIS OF TRANS-8-CHLORO-5-METHYL- 1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF</title><author>TRUSSARDI, RENE ; HOFFMANN-EMERY, FABIENNE ; PFLEGER, CHRISTOPHE ; BARTELS, BJOERN ; GRASSMANN, OLAF ; ROTHENHAEULSLER, BENNO ; HARTUNG, THOMAS ; ADAM, JEAN-MICHEL ; SCHWITTER, URS ; RAN, FREDERIC ; DIODONE, RALPH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3142754C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>TRUSSARDI, RENE</creatorcontrib><creatorcontrib>HOFFMANN-EMERY, FABIENNE</creatorcontrib><creatorcontrib>PFLEGER, CHRISTOPHE</creatorcontrib><creatorcontrib>BARTELS, BJOERN</creatorcontrib><creatorcontrib>GRASSMANN, OLAF</creatorcontrib><creatorcontrib>ROTHENHAEULSLER, BENNO</creatorcontrib><creatorcontrib>HARTUNG, THOMAS</creatorcontrib><creatorcontrib>ADAM, JEAN-MICHEL</creatorcontrib><creatorcontrib>SCHWITTER, URS</creatorcontrib><creatorcontrib>RAN, FREDERIC</creatorcontrib><creatorcontrib>DIODONE, RALPH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TRUSSARDI, RENE</au><au>HOFFMANN-EMERY, FABIENNE</au><au>PFLEGER, CHRISTOPHE</au><au>BARTELS, BJOERN</au><au>GRASSMANN, OLAF</au><au>ROTHENHAEULSLER, BENNO</au><au>HARTUNG, THOMAS</au><au>ADAM, JEAN-MICHEL</au><au>SCHWITTER, URS</au><au>RAN, FREDERIC</au><au>DIODONE, RALPH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SYNTHESIS OF TRANS-8-CHLORO-5-METHYL- 1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF</title><date>2024-01-02</date><risdate>2024</risdate><abstract>The present invention relates to a process to synthesize a compound of formula I, comprising reacting a compound of formula XII with a compound of formula XX (see formula XII)(see formula XX)(see formula XIX)(see formula I) Also disclosed are compounds useful as intermediates in the methods of the invention.
La présente invention concerne un procédé visant à synthétiser un composé de formule I comprenant une réaction entre un composé de formule XII avec un composé de formule XX (voir formule XII) [voir formule XX] (voir formule XIX) [voir formule I]. Il est également décrit des composés pouvant être utiles comme intermédiaires dans les procédés de linvention.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | SYNTHESIS OF TRANS-8-CHLORO-5-METHYL- 1-[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYSTALLINE FORMS THEREOF |
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