METHODS AND COMPOSITIONS FOR GENERATING NITRIC OXIDE AND USES THEREOF
The invention provides a combination, kit or composition comprising: (i) one or more nitrite salt; (ii) a proton source comprising one or more acid selected from organic carboxylic acids and organic non-carboxylic reducing acids; and (iii) one or more organic polyol. On reaction of the one or more n...
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| creator | WOOD, CHRISTOPHER BARRY MUNRO, HUGH SEMPLE |
| description | The invention provides a combination, kit or composition comprising: (i) one or more nitrite salt; (ii) a proton source comprising one or more acid selected from organic carboxylic acids and organic non-carboxylic reducing acids; and (iii) one or more organic polyol. On reaction of the one or more nitrite salt with the proton source in the presence of the one or more organic polyol, the combination, kit or composition provides reaction products which include nitric oxide, optionally other oxides of nitrogen and/or optionally precursors thereof and which are useful, for example, in the treatment of various disorders.
L'invention concerne un combinaison, un kit ou une composition comprenant : (I) un ou plusieurs sels de nitrite ; (ii) une source de protons comprenant un ou plusieurs acides choisis parmi les acides carboxyliques organiques et les acides réducteurs non carboxyliques organiques ; et (iii) un ou plusieurs polyols organiques. Lors de la réaction du ou des sels de nitrite avec la source de protons en présence du ou des polyols organiques, la combinaison, le kit ou la composition fournit des produits de réaction qui comprennent de l'oxyde nitrique, éventuellement d'autres oxydes d'azote et/ou éventuellement des précurseurs de ceux-ci et qui sont utiles, par exemple, dans le traitement de divers troubles. |
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L'invention concerne un combinaison, un kit ou une composition comprenant : (I) un ou plusieurs sels de nitrite ; (ii) une source de protons comprenant un ou plusieurs acides choisis parmi les acides carboxyliques organiques et les acides réducteurs non carboxyliques organiques ; et (iii) un ou plusieurs polyols organiques. Lors de la réaction du ou des sels de nitrite avec la source de protons en présence du ou des polyols organiques, la combinaison, le kit ou la composition fournit des produits de réaction qui comprennent de l'oxyde nitrique, éventuellement d'autres oxydes d'azote et/ou éventuellement des précurseurs de ceux-ci et qui sont utiles, par exemple, dans le traitement de divers troubles.</description><language>eng ; fre</language><subject>CHEMISTRY ; COMPOUNDS THEREOF ; HUMAN NECESSITIES ; HYGIENE ; INORGANIC CHEMISTRY ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NON-METALLIC ELEMENTS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201210&DB=EPODOC&CC=CA&NR=3142101A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201210&DB=EPODOC&CC=CA&NR=3142101A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WOOD, CHRISTOPHER BARRY</creatorcontrib><creatorcontrib>MUNRO, HUGH SEMPLE</creatorcontrib><title>METHODS AND COMPOSITIONS FOR GENERATING NITRIC OXIDE AND USES THEREOF</title><description>The invention provides a combination, kit or composition comprising: (i) one or more nitrite salt; (ii) a proton source comprising one or more acid selected from organic carboxylic acids and organic non-carboxylic reducing acids; and (iii) one or more organic polyol. On reaction of the one or more nitrite salt with the proton source in the presence of the one or more organic polyol, the combination, kit or composition provides reaction products which include nitric oxide, optionally other oxides of nitrogen and/or optionally precursors thereof and which are useful, for example, in the treatment of various disorders.
L'invention concerne un combinaison, un kit ou une composition comprenant : (I) un ou plusieurs sels de nitrite ; (ii) une source de protons comprenant un ou plusieurs acides choisis parmi les acides carboxyliques organiques et les acides réducteurs non carboxyliques organiques ; et (iii) un ou plusieurs polyols organiques. Lors de la réaction du ou des sels de nitrite avec la source de protons en présence du ou des polyols organiques, la combinaison, le kit ou la composition fournit des produits de réaction qui comprennent de l'oxyde nitrique, éventuellement d'autres oxydes d'azote et/ou éventuellement des précurseurs de ceux-ci et qui sont utiles, par exemple, dans le traitement de divers troubles.</description><subject>CHEMISTRY</subject><subject>COMPOUNDS THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INORGANIC CHEMISTRY</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NON-METALLIC ELEMENTS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNykEKwjAQAMBcPIj6h_2AYKwfCMmm2UOzkl3BWymynkQL9f8I4gM8zWXWDgfUwkkg1ASRhzMLKXEVyNygx4otKNUeKmmjCHylhN98ERTQgg05b93qPj0W2_3cOMiosextfo22zNPNnvYeY-j86egPPvjuj_IBLMgrZQ</recordid><startdate>20201210</startdate><enddate>20201210</enddate><creator>WOOD, CHRISTOPHER BARRY</creator><creator>MUNRO, HUGH SEMPLE</creator><scope>EVB</scope></search><sort><creationdate>20201210</creationdate><title>METHODS AND COMPOSITIONS FOR GENERATING NITRIC OXIDE AND USES THEREOF</title><author>WOOD, CHRISTOPHER BARRY ; MUNRO, HUGH SEMPLE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3142101A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>COMPOUNDS THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INORGANIC CHEMISTRY</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NON-METALLIC ELEMENTS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WOOD, CHRISTOPHER BARRY</creatorcontrib><creatorcontrib>MUNRO, HUGH SEMPLE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WOOD, CHRISTOPHER BARRY</au><au>MUNRO, HUGH SEMPLE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS AND COMPOSITIONS FOR GENERATING NITRIC OXIDE AND USES THEREOF</title><date>2020-12-10</date><risdate>2020</risdate><abstract>The invention provides a combination, kit or composition comprising: (i) one or more nitrite salt; (ii) a proton source comprising one or more acid selected from organic carboxylic acids and organic non-carboxylic reducing acids; and (iii) one or more organic polyol. On reaction of the one or more nitrite salt with the proton source in the presence of the one or more organic polyol, the combination, kit or composition provides reaction products which include nitric oxide, optionally other oxides of nitrogen and/or optionally precursors thereof and which are useful, for example, in the treatment of various disorders.
L'invention concerne un combinaison, un kit ou une composition comprenant : (I) un ou plusieurs sels de nitrite ; (ii) une source de protons comprenant un ou plusieurs acides choisis parmi les acides carboxyliques organiques et les acides réducteurs non carboxyliques organiques ; et (iii) un ou plusieurs polyols organiques. Lors de la réaction du ou des sels de nitrite avec la source de protons en présence du ou des polyols organiques, la combinaison, le kit ou la composition fournit des produits de réaction qui comprennent de l'oxyde nitrique, éventuellement d'autres oxydes d'azote et/ou éventuellement des précurseurs de ceux-ci et qui sont utiles, par exemple, dans le traitement de divers troubles.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY COMPOUNDS THEREOF HUMAN NECESSITIES HYGIENE INORGANIC CHEMISTRY MEDICAL OR VETERINARY SCIENCE METALLURGY NON-METALLIC ELEMENTS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHODS AND COMPOSITIONS FOR GENERATING NITRIC OXIDE AND USES THEREOF |
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