IDENTIFICATION OF NEOANTIGENS WITH MHC CLASS II MODEL

A method for identifying T-cells that are antigen-specific for at least one neoantigen that is likely to be presented by class II MHC alleles on surfaces of tumor cells of a subject. Peptide sequences of tumor neoantigens are obtained by sequencing the tumor cells of the subject. The peptide sequenc...

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Hauptverfasser: FRANCIS, JOSHUA MICHAEL, YOUNG, LAUREN ELIZABETH, BUSBY, JENNIFER, DAVIS, MATTHEW JOSEPH, PALMER, CHRISTINE, SKOBERNE, MOJCA, BULIK-SULLIVAN, BRENDAN, YELENSKY, ROMAN, BOUCHER, THOMAS FRANCIS, CAO, MINH DUC
Format: Patent
Sprache:eng ; fre
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