METHODS OF TREATING MULTIPLE MYELOMA
The present disclosure provides methods for treating multiple myeloma (such as refractory multiple myeloma or relapsed and refractory multiple myeloma) in an individual who received at least two prior therapies for multiple myeloma. The methods comprise administering to the individual an anti-CD38 a...
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creator | AUDAT, HELOISE CAMPANA ZAMBRANO, FRANK LE-GUENNEC, SOLENN BONESTEBE, AUDREY MANACHE-ALBERICI, LUCIE HUILLE, SYLVAIN |
description | The present disclosure provides methods for treating multiple myeloma (such as refractory multiple myeloma or relapsed and refractory multiple myeloma) in an individual who received at least two prior therapies for multiple myeloma. The methods comprise administering to the individual an anti-CD38 antibody, pomalidomide, and dexamethasone. Also provided are methods of improving renal impairment in an individual having multiple myeloma.
La présente invention concerne des méthodes de traitement du myélome multiple (tels que le myélome multiple réfractaire ou le myélome multiple avec rechute et réfractaire) chez un individu qui a reçu au moins deux thérapies antérieures pour le myélome multiple. Les méthodes selon l'invention comprennent l'administration à l'individu d'un anticorps anti-CD38, du pomalidomide et de la dexaméthasone. L'invention concerne également des méthodes permettant d'atténuer l'insuffisance rénale chez un individu présentant un myélome multiple. |
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La présente invention concerne des méthodes de traitement du myélome multiple (tels que le myélome multiple réfractaire ou le myélome multiple avec rechute et réfractaire) chez un individu qui a reçu au moins deux thérapies antérieures pour le myélome multiple. Les méthodes selon l'invention comprennent l'administration à l'individu d'un anticorps anti-CD38, du pomalidomide et de la dexaméthasone. L'invention concerne également des méthodes permettant d'atténuer l'insuffisance rénale chez un individu présentant un myélome multiple.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200806&DB=EPODOC&CC=CA&NR=3127928A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200806&DB=EPODOC&CC=CA&NR=3127928A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>AUDAT, HELOISE</creatorcontrib><creatorcontrib>CAMPANA ZAMBRANO, FRANK</creatorcontrib><creatorcontrib>LE-GUENNEC, SOLENN</creatorcontrib><creatorcontrib>BONESTEBE, AUDREY</creatorcontrib><creatorcontrib>MANACHE-ALBERICI, LUCIE</creatorcontrib><creatorcontrib>HUILLE, SYLVAIN</creatorcontrib><title>METHODS OF TREATING MULTIPLE MYELOMA</title><description>The present disclosure provides methods for treating multiple myeloma (such as refractory multiple myeloma or relapsed and refractory multiple myeloma) in an individual who received at least two prior therapies for multiple myeloma. The methods comprise administering to the individual an anti-CD38 antibody, pomalidomide, and dexamethasone. Also provided are methods of improving renal impairment in an individual having multiple myeloma.
La présente invention concerne des méthodes de traitement du myélome multiple (tels que le myélome multiple réfractaire ou le myélome multiple avec rechute et réfractaire) chez un individu qui a reçu au moins deux thérapies antérieures pour le myélome multiple. Les méthodes selon l'invention comprennent l'administration à l'individu d'un anticorps anti-CD38, du pomalidomide et de la dexaméthasone. L'invention concerne également des méthodes permettant d'atténuer l'insuffisance rénale chez un individu présentant un myélome multiple.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFDxdQ3x8HcJVvB3UwgJcnUM8fRzV_AN9QnxDPBxVfCNdPXx93XkYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxzo7GhkbmlkYWjobGRCgBAD_LIpg</recordid><startdate>20200806</startdate><enddate>20200806</enddate><creator>AUDAT, HELOISE</creator><creator>CAMPANA ZAMBRANO, FRANK</creator><creator>LE-GUENNEC, SOLENN</creator><creator>BONESTEBE, AUDREY</creator><creator>MANACHE-ALBERICI, LUCIE</creator><creator>HUILLE, SYLVAIN</creator><scope>EVB</scope></search><sort><creationdate>20200806</creationdate><title>METHODS OF TREATING MULTIPLE MYELOMA</title><author>AUDAT, HELOISE ; CAMPANA ZAMBRANO, FRANK ; LE-GUENNEC, SOLENN ; BONESTEBE, AUDREY ; MANACHE-ALBERICI, LUCIE ; HUILLE, SYLVAIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3127928A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>AUDAT, HELOISE</creatorcontrib><creatorcontrib>CAMPANA ZAMBRANO, FRANK</creatorcontrib><creatorcontrib>LE-GUENNEC, SOLENN</creatorcontrib><creatorcontrib>BONESTEBE, AUDREY</creatorcontrib><creatorcontrib>MANACHE-ALBERICI, LUCIE</creatorcontrib><creatorcontrib>HUILLE, SYLVAIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>AUDAT, HELOISE</au><au>CAMPANA ZAMBRANO, FRANK</au><au>LE-GUENNEC, SOLENN</au><au>BONESTEBE, AUDREY</au><au>MANACHE-ALBERICI, LUCIE</au><au>HUILLE, SYLVAIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS OF TREATING MULTIPLE MYELOMA</title><date>2020-08-06</date><risdate>2020</risdate><abstract>The present disclosure provides methods for treating multiple myeloma (such as refractory multiple myeloma or relapsed and refractory multiple myeloma) in an individual who received at least two prior therapies for multiple myeloma. The methods comprise administering to the individual an anti-CD38 antibody, pomalidomide, and dexamethasone. Also provided are methods of improving renal impairment in an individual having multiple myeloma.
La présente invention concerne des méthodes de traitement du myélome multiple (tels que le myélome multiple réfractaire ou le myélome multiple avec rechute et réfractaire) chez un individu qui a reçu au moins deux thérapies antérieures pour le myélome multiple. Les méthodes selon l'invention comprennent l'administration à l'individu d'un anticorps anti-CD38, du pomalidomide et de la dexaméthasone. L'invention concerne également des méthodes permettant d'atténuer l'insuffisance rénale chez un individu présentant un myélome multiple.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | METHODS OF TREATING MULTIPLE MYELOMA |
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