PYRAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USE THEREOF
Disclosed are pyrazole compounds represented by formula (I), pharmaceutical compositions containing such compounds, a method for preparing such compounds, and use of the pyrazole compounds and the pharmaceutical compositions. Such compounds are useful for inhibiting IRAK family kinases, and also use...
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| creator | XUE, CHUBIAO LI, TAO HUANG, LIYE LIU, HUABIN LI, HUA |
| description | Disclosed are pyrazole compounds represented by formula (I), pharmaceutical compositions containing such compounds, a method for preparing such compounds, and use of the pyrazole compounds and the pharmaceutical compositions. Such compounds are useful for inhibiting IRAK family kinases, and also useful for treating diseases caused by IRAK family kinases, such as autoimmune diseases, inflammatory diseases and cancers.
L'invention concerne des composés de pyrazole représentés par la formule (I), des compositions pharmaceutiques contenant de tels composés, un procédé de préparation de tels composés, et l'utilisation des composés de pyrazole et des compositions pharmaceutiques. De tels composés sont utiles pour inhiber des kinases de la famille IRAK, et sont également utiles pour traiter des maladies provoquées par des kinases de la famille IRAK, telles que des maladies auto-immunes, des maladies inflammatoires et des cancers. |
| format | Patent |
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L'invention concerne des composés de pyrazole représentés par la formule (I), des compositions pharmaceutiques contenant de tels composés, un procédé de préparation de tels composés, et l'utilisation des composés de pyrazole et des compositions pharmaceutiques. De tels composés sont utiles pour inhiber des kinases de la famille IRAK, et sont également utiles pour traiter des maladies provoquées par des kinases de la famille IRAK, telles que des maladies auto-immunes, des maladies inflammatoires et des cancers.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PYRAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USE THEREOF |
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