SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY
The present invention is related to the novel solid dispersion formulations of an anticancer compound of formula A and a process for preparing the same wherein the anticancer compound is formulated with hydrophilic polymer. The said formulation showed enhanced dissolution of the anticancer compound...
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| creator | BHARATE, SANDIP BIBISHAN MINTOO, MUBASHIR JAVED KUMAR, VIKAS MONDHE, DILIP MANIKRAO VISHWAKARMA, RAM BHARATE, SONALI SANDIP |
| description | The present invention is related to the novel solid dispersion formulations of an anticancer compound of formula A and a process for preparing the same wherein the anticancer compound is formulated with hydrophilic polymer. The said formulation showed enhanced dissolution of the anticancer compound and improved in-vivo anticancer activity. The said formulations are useful for the treatment of various types of cancer.
La présente invention concerne les nouvelles formulations de dispersion solide d'un composé anticancéreux de formule A et un procédé de préparation de celles-ci, le composé anticancéreux étant formulé avec un polymère hydrophile. Ladite formulation a présenté une dissolution améliorée du composé anticancéreux et une activité anticancéreuse in vivo améliorée. Lesdites formulations sont utiles pour le traitement de divers types de cancer. |
| format | Patent |
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La présente invention concerne les nouvelles formulations de dispersion solide d'un composé anticancéreux de formule A et un procédé de préparation de celles-ci, le composé anticancéreux étant formulé avec un polymère hydrophile. Ladite formulation a présenté une dissolution améliorée du composé anticancéreux et une activité anticancéreuse in vivo améliorée. Lesdites formulations sont utiles pour le traitement de divers types de cancer.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240319&DB=EPODOC&CC=CA&NR=3099901C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240319&DB=EPODOC&CC=CA&NR=3099901C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BHARATE, SANDIP BIBISHAN</creatorcontrib><creatorcontrib>MINTOO, MUBASHIR JAVED</creatorcontrib><creatorcontrib>KUMAR, VIKAS</creatorcontrib><creatorcontrib>MONDHE, DILIP MANIKRAO</creatorcontrib><creatorcontrib>VISHWAKARMA, RAM</creatorcontrib><creatorcontrib>BHARATE, SONALI SANDIP</creatorcontrib><title>SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY</title><description>The present invention is related to the novel solid dispersion formulations of an anticancer compound of formula A and a process for preparing the same wherein the anticancer compound is formulated with hydrophilic polymer. The said formulation showed enhanced dissolution of the anticancer compound and improved in-vivo anticancer activity. The said formulations are useful for the treatment of various types of cancer.
La présente invention concerne les nouvelles formulations de dispersion solide d'un composé anticancéreux de formule A et un procédé de préparation de celles-ci, le composé anticancéreux étant formulé avec un polymère hydrophile. Ladite formulation a présenté une dissolution améliorée du composé anticancéreux et une activité anticancéreuse in vivo améliorée. Lesdites formulations sont utiles pour le traitement de divers types de cancer.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgP9vfxdFFw8QwOcA0K9vT3U3D29w0I8gz29HNXcPQDohBPZ0c_Z9cgsIR_qJ-Lgpt_kIInUJF_mKuLAlB_qJOnj2dIJFCti4KrmxtQvXMkDwNrWmJOcSovlOZmkHdzDXH20E0tyI9PLS5ITE7NSy2Jd3Y0NrC0tDQwdDYmrAIAIuwwTg</recordid><startdate>20240319</startdate><enddate>20240319</enddate><creator>BHARATE, SANDIP BIBISHAN</creator><creator>MINTOO, MUBASHIR JAVED</creator><creator>KUMAR, VIKAS</creator><creator>MONDHE, DILIP MANIKRAO</creator><creator>VISHWAKARMA, RAM</creator><creator>BHARATE, SONALI SANDIP</creator><scope>EVB</scope></search><sort><creationdate>20240319</creationdate><title>SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY</title><author>BHARATE, SANDIP BIBISHAN ; MINTOO, MUBASHIR JAVED ; KUMAR, VIKAS ; MONDHE, DILIP MANIKRAO ; VISHWAKARMA, RAM ; BHARATE, SONALI SANDIP</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3099901C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>BHARATE, SANDIP BIBISHAN</creatorcontrib><creatorcontrib>MINTOO, MUBASHIR JAVED</creatorcontrib><creatorcontrib>KUMAR, VIKAS</creatorcontrib><creatorcontrib>MONDHE, DILIP MANIKRAO</creatorcontrib><creatorcontrib>VISHWAKARMA, RAM</creatorcontrib><creatorcontrib>BHARATE, SONALI SANDIP</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BHARATE, SANDIP BIBISHAN</au><au>MINTOO, MUBASHIR JAVED</au><au>KUMAR, VIKAS</au><au>MONDHE, DILIP MANIKRAO</au><au>VISHWAKARMA, RAM</au><au>BHARATE, SONALI SANDIP</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY</title><date>2024-03-19</date><risdate>2024</risdate><abstract>The present invention is related to the novel solid dispersion formulations of an anticancer compound of formula A and a process for preparing the same wherein the anticancer compound is formulated with hydrophilic polymer. The said formulation showed enhanced dissolution of the anticancer compound and improved in-vivo anticancer activity. The said formulations are useful for the treatment of various types of cancer.
La présente invention concerne les nouvelles formulations de dispersion solide d'un composé anticancéreux de formule A et un procédé de préparation de celles-ci, le composé anticancéreux étant formulé avec un polymère hydrophile. Ladite formulation a présenté une dissolution améliorée du composé anticancéreux et une activité anticancéreuse in vivo améliorée. Lesdites formulations sont utiles pour le traitement de divers types de cancer.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY |
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