ANTICOAGULANT PROTEINS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH THE ACTIVATION OF NEUTROPHILS
The present invention relates to a protein or polypeptide comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, and its use for inhibiting the extrinsic coagulation pathway and for treating and/or preventing diseases and conditions associated to the recruitment an...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | DEMOULIN, STEPHANIE DEROCHETTE, SANDRINE GODFROID, EDMOND GUYAUX, MICHEL PIREAUX, VALERIE TASSIGNON, JOEL |
| description | The present invention relates to a protein or polypeptide comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, and its use for inhibiting the extrinsic coagulation pathway and for treating and/or preventing diseases and conditions associated to the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway. In particular, the present invention relates to the use of a protein comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, for the treatment and/or prevention of any thrombotic events associated with the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway.
La présente invention concerne une protéine ou un polypeptide comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, et son utilisation pour inhiber la voie de coagulation extrinsèque et pour traiter et/ou prévenir des maladies et des états pathologiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque. En particulier, la présente invention concerne l'utilisation d'une protéine comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, pour le traitement et/ou la prévention d'éventuels événements thrombotiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA3089358A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA3089358A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA3089358A13</originalsourceid><addsrcrecordid>eNqNysEKgkAQgGEvHaJ6h3mBoJDAjsM6ugOyIztjHkVio0OUYO9PBj1Ap_8_fOvsjsHYCdZdsxy0UYw4KGAowTxxhE4JKolgkdA41FCyEiotRlUco1EJPZv_ekBnfFmcBJAKAnUWpfXc6DZb3cbHnHa_bjKoyJzfp-k1pHkar-mZ3oPD_FCc81OBx_wP8gHanjVu</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ANTICOAGULANT PROTEINS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH THE ACTIVATION OF NEUTROPHILS</title><source>esp@cenet</source><creator>DEMOULIN, STEPHANIE ; DEROCHETTE, SANDRINE ; GODFROID, EDMOND ; GUYAUX, MICHEL ; PIREAUX, VALERIE ; TASSIGNON, JOEL</creator><creatorcontrib>DEMOULIN, STEPHANIE ; DEROCHETTE, SANDRINE ; GODFROID, EDMOND ; GUYAUX, MICHEL ; PIREAUX, VALERIE ; TASSIGNON, JOEL</creatorcontrib><description>The present invention relates to a protein or polypeptide comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, and its use for inhibiting the extrinsic coagulation pathway and for treating and/or preventing diseases and conditions associated to the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway. In particular, the present invention relates to the use of a protein comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, for the treatment and/or prevention of any thrombotic events associated with the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway.
La présente invention concerne une protéine ou un polypeptide comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, et son utilisation pour inhiber la voie de coagulation extrinsèque et pour traiter et/ou prévenir des maladies et des états pathologiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque. En particulier, la présente invention concerne l'utilisation d'une protéine comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, pour le traitement et/ou la prévention d'éventuels événements thrombotiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190808&DB=EPODOC&CC=CA&NR=3089358A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190808&DB=EPODOC&CC=CA&NR=3089358A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DEMOULIN, STEPHANIE</creatorcontrib><creatorcontrib>DEROCHETTE, SANDRINE</creatorcontrib><creatorcontrib>GODFROID, EDMOND</creatorcontrib><creatorcontrib>GUYAUX, MICHEL</creatorcontrib><creatorcontrib>PIREAUX, VALERIE</creatorcontrib><creatorcontrib>TASSIGNON, JOEL</creatorcontrib><title>ANTICOAGULANT PROTEINS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH THE ACTIVATION OF NEUTROPHILS</title><description>The present invention relates to a protein or polypeptide comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, and its use for inhibiting the extrinsic coagulation pathway and for treating and/or preventing diseases and conditions associated to the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway. In particular, the present invention relates to the use of a protein comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, for the treatment and/or prevention of any thrombotic events associated with the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway.
La présente invention concerne une protéine ou un polypeptide comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, et son utilisation pour inhiber la voie de coagulation extrinsèque et pour traiter et/ou prévenir des maladies et des états pathologiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque. En particulier, la présente invention concerne l'utilisation d'une protéine comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, pour le traitement et/ou la prévention d'éventuels événements thrombotiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNysEKgkAQgGEvHaJ6h3mBoJDAjsM6ugOyIztjHkVio0OUYO9PBj1Ap_8_fOvsjsHYCdZdsxy0UYw4KGAowTxxhE4JKolgkdA41FCyEiotRlUco1EJPZv_ekBnfFmcBJAKAnUWpfXc6DZb3cbHnHa_bjKoyJzfp-k1pHkar-mZ3oPD_FCc81OBx_wP8gHanjVu</recordid><startdate>20190808</startdate><enddate>20190808</enddate><creator>DEMOULIN, STEPHANIE</creator><creator>DEROCHETTE, SANDRINE</creator><creator>GODFROID, EDMOND</creator><creator>GUYAUX, MICHEL</creator><creator>PIREAUX, VALERIE</creator><creator>TASSIGNON, JOEL</creator><scope>EVB</scope></search><sort><creationdate>20190808</creationdate><title>ANTICOAGULANT PROTEINS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH THE ACTIVATION OF NEUTROPHILS</title><author>DEMOULIN, STEPHANIE ; DEROCHETTE, SANDRINE ; GODFROID, EDMOND ; GUYAUX, MICHEL ; PIREAUX, VALERIE ; TASSIGNON, JOEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3089358A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DEMOULIN, STEPHANIE</creatorcontrib><creatorcontrib>DEROCHETTE, SANDRINE</creatorcontrib><creatorcontrib>GODFROID, EDMOND</creatorcontrib><creatorcontrib>GUYAUX, MICHEL</creatorcontrib><creatorcontrib>PIREAUX, VALERIE</creatorcontrib><creatorcontrib>TASSIGNON, JOEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DEMOULIN, STEPHANIE</au><au>DEROCHETTE, SANDRINE</au><au>GODFROID, EDMOND</au><au>GUYAUX, MICHEL</au><au>PIREAUX, VALERIE</au><au>TASSIGNON, JOEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTICOAGULANT PROTEINS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH THE ACTIVATION OF NEUTROPHILS</title><date>2019-08-08</date><risdate>2019</risdate><abstract>The present invention relates to a protein or polypeptide comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, and its use for inhibiting the extrinsic coagulation pathway and for treating and/or preventing diseases and conditions associated to the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway. In particular, the present invention relates to the use of a protein comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, for the treatment and/or prevention of any thrombotic events associated with the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway.
La présente invention concerne une protéine ou un polypeptide comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, et son utilisation pour inhiber la voie de coagulation extrinsèque et pour traiter et/ou prévenir des maladies et des états pathologiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque. En particulier, la présente invention concerne l'utilisation d'une protéine comprenant un polypeptide de glande salivaire Ixodes ricinus, un fragment ou un variant de celui-ci, pour le traitement et/ou la prévention d'éventuels événements thrombotiques associés au recrutement et à l'activation de neutrophiles après l'activation de la voie de coagulation extrinsèque.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_CA3089358A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ANTICOAGULANT PROTEINS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH THE ACTIVATION OF NEUTROPHILS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T02%3A38%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DEMOULIN,%20STEPHANIE&rft.date=2019-08-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA3089358A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |