COMPOUND 5-[3-(2,5-DICHLORO-4,6-DIMETHYL-1-OXY-PYRIDIN-3-YL)-[1,2,4]OXADIAZOL-5-YL]-3-NITROBENZENE-1,2-DIOL IN MICROPARTICULATE FORM AND ITS USE IN THE TREATMENT OF PARKINSON'S DISEASE

There is disclosed a crystalline compound of formula (II) (see formula II) in microparticulate form having a particle size specification with D10 equivalent circle diameter not less than 4 pm, a D50 equivalent circle diameter of 10-45 µm and a D95 equivalent circle diameter of not more than 80 µm. T...

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Bibliographische Detailangaben
Hauptverfasser:	LEARMONTH, DAVID ALEXANDER, REITER, KLAUS, SCHLUMMER, BJOERN, KISS, LASZLO ERNO, ZIMMERMAN, AXEL, RUSSO, DOMENICO, WAHNON, JORGE BRUNO REIS, ESZENYI, TIBOR, KREIS, MICHAEL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	There is disclosed a crystalline compound of formula (II) (see formula II) in microparticulate form having a particle size specification with D10 equivalent circle diameter not less than 4 pm, a D50 equivalent circle diameter of 10-45 µm and a D95 equivalent circle diameter of not more than 80 µm. The compound of the invention is useful in the treatment of Parkinson's disease. Un composé cristallin est de formule (II) [voir la formule II] est décrit, lequel est de forme microparticulaire ayant une spécification de dimension de particules ayant un diamètre de cercle équivalent à D10 dau moins 4 pm, un diamètre de cercle équivalent à D50 de 10 à 45 µm et un diamètre de cercle équivalent à D95 dau plus 80 µm. Le composé de linvention est utile dans le traitement de la maladie de Parkinson.