1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS
The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herin. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the prolifera...
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| creator | QI, YINGMEI YANG, HONG CAI, ZHENHONG R XU, LIANHONG HAN, XIAOCHUN JABRI, SALMAN Y XU, JIE GONZALEZ BUENROSTRO, ANA ZURISADAI CHO, AESOP MCFADDEN, RYAN VOIGT, JOHANNES |
| description | The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herin. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I.
La présente invention concerne un composé de formule I : ou un sel pharmaceutiquement acceptable de celui-ci. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule I, des procédés de préparation de composés de formule I, des procédés thérapeutiques pour traiter la prolifération du virus VIH, traiter le SIDA ou retarder l'apparition des symptômes du SIDA chez un mammifère à l'aide des composés de formule I. |
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La présente invention concerne un composé de formule I : ou un sel pharmaceutiquement acceptable de celui-ci. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule I, des procédés de préparation de composés de formule I, des procédés thérapeutiques pour traiter la prolifération du virus VIH, traiter le SIDA ou retarder l'apparition des symptômes du SIDA chez un mammifère à l'aide des composés de formule I.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240326&DB=EPODOC&CC=CA&NR=3076761C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240326&DB=EPODOC&CC=CA&NR=3076761C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>QI, YINGMEI</creatorcontrib><creatorcontrib>YANG, HONG</creatorcontrib><creatorcontrib>CAI, ZHENHONG R</creatorcontrib><creatorcontrib>XU, LIANHONG</creatorcontrib><creatorcontrib>HAN, XIAOCHUN</creatorcontrib><creatorcontrib>JABRI, SALMAN Y</creatorcontrib><creatorcontrib>XU, JIE</creatorcontrib><creatorcontrib>GONZALEZ BUENROSTRO, ANA ZURISADAI</creatorcontrib><creatorcontrib>CHO, AESOP</creatorcontrib><creatorcontrib>MCFADDEN, RYAN</creatorcontrib><creatorcontrib>VOIGT, JOHANNES</creatorcontrib><title>1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS</title><description>The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herin. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I.
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La présente invention concerne un composé de formule I : ou un sel pharmaceutiquement acceptable de celui-ci. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule I, des procédés de préparation de composés de formule I, des procédés thérapeutiques pour traiter la prolifération du virus VIH, traiter le SIDA ou retarder l'apparition des symptômes du SIDA chez un mammifère à l'aide des composés de formule I.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS |
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