CRYSTALLINE FORMS OF 5-BROMO-2,6-DI(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE AND NEW SALTS
This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water ("hydrates"). These materials are useful in the t...
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| creator | CUI, KAI CASTRO-PALOMINO LARIA, JULIO CESAR KONG, WEIYONG |
| description | This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water ("hydrates"). These materials are useful in the treatment of various diseases, including carcinomas, specifically lung cancer and more specifically non-small cell lung cancer.
La présente invention concerne diverses formes cristallines de 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine et un sel de celles-ci, ainsi que des compositions et des procédés d'utilisation de celles-ci. Dans certains modes de réalisation, les formes cristallines contiennent également de l'eau ("hydrates"). Les matériaux de l'invention sont utiles dans le traitement de diverses maladies, y compris des carcinomes, en particulier le cancer du poumon et plus particulièrement le cancer du poumon non à petites cellules. |
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La présente invention concerne diverses formes cristallines de 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine et un sel de celles-ci, ainsi que des compositions et des procédés d'utilisation de celles-ci. Dans certains modes de réalisation, les formes cristallines contiennent également de l'eau ("hydrates"). Les matériaux de l'invention sont utiles dans le traitement de diverses maladies, y compris des carcinomes, en particulier le cancer du poumon et plus particulièrement le cancer du poumon non à petites cellules.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181206&DB=EPODOC&CC=CA&NR=3065475A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181206&DB=EPODOC&CC=CA&NR=3065475A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CUI, KAI</creatorcontrib><creatorcontrib>CASTRO-PALOMINO LARIA, JULIO CESAR</creatorcontrib><creatorcontrib>KONG, WEIYONG</creatorcontrib><title>CRYSTALLINE FORMS OF 5-BROMO-2,6-DI(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE AND NEW SALTS</title><description>This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water ("hydrates"). These materials are useful in the treatment of various diseases, including carcinomas, specifically lung cancer and more specifically non-small cell lung cancer.
La présente invention concerne diverses formes cristallines de 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine et un sel de celles-ci, ainsi que des compositions et des procédés d'utilisation de celles-ci. Dans certains modes de réalisation, les formes cristallines contiennent également de l'eau ("hydrates"). Les matériaux de l'invention sont utiles dans le traitement de diverses maladies, y compris des carcinomes, en particulier le cancer du poumon et plus particulièrement le cancer du poumon non à petites cellules.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAh2DooMDnH08fH0c1Vw8w_yDVbwd1Mw1XUK8vf11zXSMdN18dQw9NANiAxyjPL30TXUjfTRBHI8fT1dPP10TXQdfUE6Hf1cFPxcwxWCHX1CgnkYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSbyzo7GBmamJuamjoTERSgA6bC6H</recordid><startdate>20181206</startdate><enddate>20181206</enddate><creator>CUI, KAI</creator><creator>CASTRO-PALOMINO LARIA, JULIO CESAR</creator><creator>KONG, WEIYONG</creator><scope>EVB</scope></search><sort><creationdate>20181206</creationdate><title>CRYSTALLINE FORMS OF 5-BROMO-2,6-DI(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE AND NEW SALTS</title><author>CUI, KAI ; CASTRO-PALOMINO LARIA, JULIO CESAR ; KONG, WEIYONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3065475A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CUI, KAI</creatorcontrib><creatorcontrib>CASTRO-PALOMINO LARIA, JULIO CESAR</creatorcontrib><creatorcontrib>KONG, WEIYONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CUI, KAI</au><au>CASTRO-PALOMINO LARIA, JULIO CESAR</au><au>KONG, WEIYONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CRYSTALLINE FORMS OF 5-BROMO-2,6-DI(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE AND NEW SALTS</title><date>2018-12-06</date><risdate>2018</risdate><abstract>This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water ("hydrates"). These materials are useful in the treatment of various diseases, including carcinomas, specifically lung cancer and more specifically non-small cell lung cancer.
La présente invention concerne diverses formes cristallines de 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine et un sel de celles-ci, ainsi que des compositions et des procédés d'utilisation de celles-ci. Dans certains modes de réalisation, les formes cristallines contiennent également de l'eau ("hydrates"). Les matériaux de l'invention sont utiles dans le traitement de diverses maladies, y compris des carcinomes, en particulier le cancer du poumon et plus particulièrement le cancer du poumon non à petites cellules.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CRYSTALLINE FORMS OF 5-BROMO-2,6-DI(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE AND NEW SALTS |
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