METHOD OF PREPARING BENZYL 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PICOLINATE

A method of preparing benzyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (I) from benzyl 4,5-difluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (II) is described. The method includes the use of amination and chlorination process steps to provide the compound of Fo...

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Hauptverfasser: MURDOCH, BRIAN, FISK, JASON S, COULING, DAVID J, DONALDSON, MEGAN E, SCHUITMAN, ABRAHAM D, LENG, RONALD B
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creator MURDOCH, BRIAN
FISK, JASON S
COULING, DAVID J
DONALDSON, MEGAN E
SCHUITMAN, ABRAHAM D
LENG, RONALD B
description A method of preparing benzyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (I) from benzyl 4,5-difluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (II) is described. The method includes the use of amination and chlorination process steps to provide the compound of Formula I. L'invention concerne un procédé de préparation de benzyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-méthoxyphényl)picolinate (I) à partir de benzyl 4,5-difluoro-6-(4-chloro-2-fluoro-3-méthoxyphényl)picolinate (II). Le procédé comprend l'utilisation d'étapes de traitement d'amination et de chloration pour fournir le composé de formule I.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title METHOD OF PREPARING BENZYL 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PICOLINATE
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