7-PHENYLETHYLAMINO-4H-PYRIMIDO[4,5-D][1,3]OXAZIN-2-ONE COMPOUNDS AS MUTANT IDH1 AND IDH2 INHIBITORS

The present invention relates to mutant IDH1 or mutant IDH2 enzyme inhibitors of Fonnula I or Ia, as defined herein, and their use in the treatment of cancer expressing mutant IDH1 or IDH2 such as fibrosarcoma, acute myeloid leukemia, glioma or glioblastoma. The present invention also relates to pha...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	GILMOUR, RAYMOND, HAHN, PATRIC JAMES, RANKOVIC, ZORAN, BAUER, RENATO ALEJANDRO, BOULET, SERGE LOUIS, BURKHOLDER, TIMOTHY PAUL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!