METHOD FOR DETERMINING THE HAEMOGLOBIN F CONTENT OF AN ERYTHROID CELL

The invention concerns a method for determining, by flow cytometry, the haemoglobin F (HbF) content of each erythroid cell of a set of erythroid cells. This method applies in particular to determining the HbF content of each red blood cell of a set of red blood cells. The invention also concerns a m...

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Hauptverfasser: CAMBOT, MARIE, VANDEMEULEBROUCK, GAETANA, GALACTEROS, FREDERIC, RAKOTOSON, MARIE GEORGINE, NOIZAT PIRENNE, FRANCE, BARTOLUCCI, PABLO
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creator CAMBOT, MARIE
VANDEMEULEBROUCK, GAETANA
GALACTEROS, FREDERIC
RAKOTOSON, MARIE GEORGINE
NOIZAT PIRENNE, FRANCE
BARTOLUCCI, PABLO
description The invention concerns a method for determining, by flow cytometry, the haemoglobin F (HbF) content of each erythroid cell of a set of erythroid cells. This method applies in particular to determining the HbF content of each red blood cell of a set of red blood cells. The invention also concerns a method for determining the quantity of red blood cells transfused into a patient, and for monitoring the therapeutic effectiveness of a treatment for sickle cell disease or ß-thalassemia. L'invention concerne un procédé de détermination par cytométrie de flux de la teneur en hémoglobine F (HbF) de chaque cellule érythroïde d'un ensemble de cellules érythroïdes. Ce procédé s'applique notamment à la détermination de la teneur en HbF de chaque globule rouge d'un ensemble de globules rouges. L'invention concerne également un procédé de détermination de la quantité de globules rouges transfusés chez un patient, et de suivi de l'efficacité thérapeutique d'un traitement de la drépanocytose ou de la ß-thalassémie.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title METHOD FOR DETERMINING THE HAEMOGLOBIN F CONTENT OF AN ERYTHROID CELL
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