INSULIN ANALOGS

The present invention relates to insulin analogs, particularly insulin analogs having shortened B chains. The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and desi...

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Hauptverfasser:	SMITH, BRIAN, CHOU, DANNY HUNGIEH, LAWRENCE, MICHAEL COLIN, MENTING, JOHN GERBRANDT TASMAN, SAFAVI-HEMAMI, HELENA, BALDOMERO, OLIVERA M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	SMITH, BRIAN CHOU, DANNY HUNGIEH LAWRENCE, MICHAEL COLIN MENTING, JOHN GERBRANDT TASMAN SAFAVI-HEMAMI, HELENA BALDOMERO, OLIVERA M
description	The present invention relates to insulin analogs, particularly insulin analogs having shortened B chains. The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and design insulin analogs that interact with or modulate the insulin receptor. The present invention also relates to therapeutic and prophylactic methods using insulin analogs. La présente invention concerne des analogues de l'insuline, en particulier des analogues de l'insuline présentant des chaînes B raccourcies. La présente invention concerne également la structure cristalline de l'insuline provenant du venin d'escargots marins, ainsi que des procédés d'utilisation du cristal et des informations structurales associées pour cribler et concevoir des analogues d'insuline qui interagissent avec ou modulent le récepteur de l'insuline. La présente invention concerne également des procédés thérapeutiques et prophylactiques utilisant les analogues de l'insuline.
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The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and design insulin analogs that interact with or modulate the insulin receptor. The present invention also relates to therapeutic and prophylactic methods using insulin analogs. La présente invention concerne des analogues de l'insuline, en particulier des analogues de l'insuline présentant des chaînes B raccourcies. La présente invention concerne également la structure cristalline de l'insuline provenant du venin d'escargots marins, ainsi que des procédés d'utilisation du cristal et des informations structurales associées pour cribler et concevoir des analogues d'insuline qui interagissent avec ou modulent le récepteur de l'insuline. 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The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and design insulin analogs that interact with or modulate the insulin receptor. The present invention also relates to therapeutic and prophylactic methods using insulin analogs. La présente invention concerne des analogues de l'insuline, en particulier des analogues de l'insuline présentant des chaînes B raccourcies. La présente invention concerne également la structure cristalline de l'insuline provenant du venin d'escargots marins, ainsi que des procédés d'utilisation du cristal et des informations structurales associées pour cribler et concevoir des analogues d'insuline qui interagissent avec ou modulent le récepteur de l'insuline. 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subjects	CHEMISTRY HUMAN NECESSITIES HYGIENE INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title	INSULIN ANALOGS
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