METHODS OF PRODUCING IN VITRO LIVER CONSTRUCTS AND USES THEREOF

Provided herein are cell compositions useful for making artificial liver constructs. The cell composition my include, in combination, (a) hepatocyte cells, (b) Kuppfer cells, (c) hepatic stellate cells, (d) sinusoidal endothelial cells, and (e) cholangiocyte cells. L'invention concerne des comp...

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Bibliographische Detailangaben
Hauptverfasser:	ATALA, ANTHONY, BISHOP, COLIN, MEAD, IVY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein are cell compositions useful for making artificial liver constructs. The cell composition my include, in combination, (a) hepatocyte cells, (b) Kuppfer cells, (c) hepatic stellate cells, (d) sinusoidal endothelial cells, and (e) cholangiocyte cells. L'invention concerne des compositions de cellules utiles pour fabriquer des constructions de foie artificiel. La composition cellulaire peut comprendre, en combinaison, (a) des cellules hépatiques, (b) des cellules de Kuppfer, (c) des cellules stellaires hépatiques, (d) des cellules endothéliales sinusoïdales, et (e) des cholangiocytes.