THERAPEUTIC COMBINATIONS OF ORALLY ADMINISTERED PACLITAXEL AND A P-GP INHIBITOR FOR THE TREATMENT OF CANCER
The application pertains to pharmaceutical combinations of orally administered paclitaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity -type infusion reactions, and other negative...
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| creator | FETTERLY, GERALK KRAMER, E JACKSON, CHRISTOPHER GLYN CHARLES KWAN, MIN-FUN GLUE, PAUL HUNG, CHEUNG-TAK |
| description | The application pertains to pharmaceutical combinations of orally administered paclitaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity -type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered paclitaxel (e.g., Taxol® or paclitaxel formulated with Cremophor®) therapy in a subject suffering from cancer.
La présente demande concerne des combinaisons pharmaceutiques de paclitaxel et d'un inhibiteur de P-gp à usage oral. Ces combinaisons pharmaceutiques sont utiles pour traiter le cancer chez un sujet et pour réduire ou prévenir la toxicité, les réactions aux perfusions de type hypersensibilité, et autres effets secondaires négatifs résultant de, ou associés à une thérapie basée sur le paclitaxel administré par voie intraveineuse (par exemple, Taxol® ou paclitaxel formulé avec du Cremophor®) chez un sujet souffrant d'un cancer. |
| format | Patent |
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La présente demande concerne des combinaisons pharmaceutiques de paclitaxel et d'un inhibiteur de P-gp à usage oral. Ces combinaisons pharmaceutiques sont utiles pour traiter le cancer chez un sujet et pour réduire ou prévenir la toxicité, les réactions aux perfusions de type hypersensibilité, et autres effets secondaires négatifs résultant de, ou associés à une thérapie basée sur le paclitaxel administré par voie intraveineuse (par exemple, Taxol® ou paclitaxel formulé avec du Cremophor®) chez un sujet souffrant d'un cancer.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231017&DB=EPODOC&CC=CA&NR=2993127C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231017&DB=EPODOC&CC=CA&NR=2993127C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FETTERLY, GERALK</creatorcontrib><creatorcontrib>KRAMER, E</creatorcontrib><creatorcontrib>JACKSON, CHRISTOPHER GLYN CHARLES</creatorcontrib><creatorcontrib>KWAN, MIN-FUN</creatorcontrib><creatorcontrib>GLUE, PAUL</creatorcontrib><creatorcontrib>HUNG, CHEUNG-TAK</creatorcontrib><title>THERAPEUTIC COMBINATIONS OF ORALLY ADMINISTERED PACLITAXEL AND A P-GP INHIBITOR FOR THE TREATMENT OF CANCER</title><description>The application pertains to pharmaceutical combinations of orally administered paclitaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity -type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered paclitaxel (e.g., Taxol® or paclitaxel formulated with Cremophor®) therapy in a subject suffering from cancer.
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La présente demande concerne des combinaisons pharmaceutiques de paclitaxel et d'un inhibiteur de P-gp à usage oral. Ces combinaisons pharmaceutiques sont utiles pour traiter le cancer chez un sujet et pour réduire ou prévenir la toxicité, les réactions aux perfusions de type hypersensibilité, et autres effets secondaires négatifs résultant de, ou associés à une thérapie basée sur le paclitaxel administré par voie intraveineuse (par exemple, Taxol® ou paclitaxel formulé avec du Cremophor®) chez un sujet souffrant d'un cancer.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THERAPEUTIC COMBINATIONS OF ORALLY ADMINISTERED PACLITAXEL AND A P-GP INHIBITOR FOR THE TREATMENT OF CANCER |
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