IN VITRO DIAGNOSTIC METHOD FOR ALZHEIMER'S DISEASE, BASED ON THE ALBUMIN REDOX LEVEL IN THE CEREBROSPINAL FLUID

The present invention relates to an in vitro method for diagnosing Alzheimer's disease (AD), comprising the steps of: a) determining the content of mercaptoalbumin (HMA) in a sample of cerebrospinal fluid (CSF); and b) comparing the content determined with the content of HMA in CSF in healthy s...

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Bibliographische Detailangaben
Hauptverfasser:	ORTIZ FERNANDEZ, ANA MARIA, GRANCHA GAMON, SALVADOR, COSTA RIEROLA, MONTSERRAT
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	The present invention relates to an in vitro method for diagnosing Alzheimer's disease (AD), comprising the steps of: a) determining the content of mercaptoalbumin (HMA) in a sample of cerebrospinal fluid (CSF); and b) comparing the content determined with the content of HMA in CSF in healthy subjects. lf the HMA content is less than that of the healthy subjects, it is indicative of AD. La présente invention porte sur une méthode de diagnostic in vitro de la maladie dAlzheimer qui comprend les étapes suivantes : a) déterminer la teneur en mercaptoalbumine (HMA) dun échantillon de liquide céphalorachidien (LCR); b) comparer la teneur en HMA déterminée à la teneur en HMA du LCR dun sujet en santé. Si la teneur en HMA est inférieure à celle dun sujet en santé, cela indique la présence de la maladie dAlzheimer.